Several adipocyte-secreted factors have been demonstrated to potentially link obesity,
insulin resistance, and cardiovascular disease. Among those, adiponectin is an insulin …

Adiponectin is the most abundant adipose-specific protein. Its expression is reduced in
obesity, insulin resistance and type 2 diabetes, and plasma concentrations are inversely …

Nearly 1 in 4 adults in the United States is obese. The connection between obesity and
insulin resistance, type 2 diabetes, and cardiovascular disease is a well researched one …

Under disease conditions including obesity (insulin resistance) and diabetes, dysregulation
of adipokines such as tumor necrosis factor (TNF)-α, leptin, resistin, and adiponectin …

Adiponectin and adiponectin receptors (AdipoRs) have been found to play significant roles
in the etiology of obesity-related chronic disease. Their discovery has been a long and …

Adiponectin is produced predominantly by adipocytes and plays an important role in
metabolic and cardiovascular homeostasis through its insulin-sensitizing actions and anti …

Obesity and its related disorders, glucose intolerance, hypertension and hyperlipidemia,
collectively named the metabolic syndrome, result in substantial cardiovascular morbidity …

The global epidemic of obesity is accompanied by an increased prevalence of
cardiovascular disease (CVD), in particular stroke and heart attack. Dysfunctional adipose …

Recent studies emphasize the role played by adiponectin in the homeostasis of adipose
tissue and in the pathogenesis of the metabolic syndrome, type 2 diabetes, and …

Studies performed during the last decade indicate that adipose tissue is not only a site of
triglyceride storage but also an active endocrine organ which secretes many biologically …