Role of oxidative stresses induced by diesel exhaust particles in airway inflammation, allergy and asthma: their potential as a target of chemoprevention

YJ Li, H Takizawa, T Kawada - Inflammation & Allergy-Drug …, 2010 - ingentaconnect.com
Epidemiological studies have shown that particulate air pollutants, such as diesel exhaust
particles (DEPs) are implicated in the increased incidence of allergic airway disorders. DEPs …

Nrf2 is a protective factor against oxidative stresses induced by diesel exhaust particle in allergic asthma

YJ Li, T Kawada, A Azuma - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Epidemiological studies have shown that air pollutants, such as diesel exhaust particle
(DEP), are implicated in the increased incidence of allergic airway disorders. In vitro studies …

Enhancement of allergic inflammation by diesel exhaust particles: permissive role of reactive oxygen species

AM Casillas, T Hiura, N Li, AE Nel - Annals of Allergy, Asthma & …, 1999 - Elsevier
BACKGROUND: Diesel emission particulates (DEP) exert effects on the immune system and
act as an adjuvant which enhances allergic inflammation. Animal and human models have …

Diesel exhaust particles and their effect on induced cytokine expression in human bronchial epithelial cells

H Takizawa - Current opinion in allergy and clinical immunology, 2004 - journals.lww.com
Host responses to DEPs are regulated by a balance between antioxidants and
proinflammatory responses. DEP-induced oxidants play a key role in proinflammatory …

Biology of diesel exhaust effects on respiratory function

M Riedl, D Diaz-Sanchez - Journal of Allergy and Clinical Immunology, 2005 - Elsevier
In recent decades, clinicians and scientists have witnessed a significant increase in the
prevalence of allergic rhinitis and asthma. The factors underlying this phenomenon are …

The dual effect of the particulate and organic components of diesel exhaust particles on the alteration of pulmonary immune/inflammatory responses and metabolic …

JYC Ma, JKH Ma - Journal of Environmental Science and Health …, 2002 - Taylor & Francis
Exposure to diesel exhaust particles (DEP) is an environmental and occupational health
concern. This review examines the cellular actions of the organic and the particulate …

Diesel exhausts particles: Their role in increasing the incidence of asthma. Reviewing the evidence of a causal link

X Muñoz, E Barreiro, V Bustamante… - Science of the Total …, 2019 - Elsevier
Exposure to air pollutants has been correlated with an increase in the severity of asthma and
in the exacerbation of pre-existing asthma. However, whether or not environmental pollution …

Antioxidant enzyme induction: a new protective approach against the adverse effects of diesel exhaust particles

J Wan, D Diaz-Sanchez - Inhalation toxicology, 2007 - Taylor & Francis
Exposure to airborne particulate pollutants such as diesel exhaust particles (DEPs) has
been associated with allergic respiratory disorders, including asthma and allergic rhinitis. In …

The effects of oxidative stress induced by prolonged low-dose diesel exhaust particle exposure on the generation of allergic airway inflammation differ between BALB …

YJ Li, H Takizawa, A Azuma, T Kohyama… - …, 2009 - Taylor & Francis
We have recently reported that airway inflammatory responses to the oxidative stress
induced by prolonged low-dose diesel exhaust particle (DEP) exposure differ markedly …

Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice

YJ Li, H Takizawa, A Azuma, T Kohyama… - Clinical …, 2008 - Elsevier
To test our hypothesis that diesel exhaust particle (DEP)-induced oxidative stress and host
antioxidant responses play a key role in the development of DEP-induced airway …