Particulate matter induces translocation of IL-6 from the lung to the systemic circulation

T Kido, E Tamagawa, N Bai, K Suda… - American journal of …, 2011 - atsjournals.org
The biological mechanisms responsible for an association between elevated concentrations
of ambient particulate matter (PM) and increased cardiovascular morbidity and mortality …

Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction

E Tamagawa, N Bai, K Morimoto… - … of Physiology-Lung …, 2008 - journals.physiology.org
Epidemiologic and animal studies have shown that exposure to particulate matter air
pollution (PM) is a risk factor for the development of atherosclerosis. Whether PM-induced …

Particulate matter induces cytokine expression in human bronchial epithelial cells

T Fujii, S Hayashi, JC Hogg, R Vincent… - American journal of …, 2001 - atsjournals.org
The present study was designed to determine cytokines produced by primary human
bronchial epithelial cells (HBECs) exposed to ambient air pollution particles (EHC-93) …

Exposure to fine particulate air pollution is associated with endothelial injury and systemic inflammation

CA Pope III, A Bhatnagar, JP McCracken… - Circulation …, 2016 - Am Heart Assoc
Rationale: Epidemiological evidence indicates that exposures to fine particulate matter air
pollution (PM2. 5) contribute to global burden of disease, primarily as a result of increased …

Health effects and time course of particulate matter on the cardiopulmonary system in rats with lung inflammation

MMW Ulrich, GM Alink, P Kumarathasan… - Journal of Toxicology …, 2002 - Taylor & Francis
Recent epidemiological studies associate health effects and particulate matter in ambient
air. Exacerbation of the particle-induced inflammation can be a mechanism responsible for …

Contribution of lung macrophages to the inflammatory responses induced by exposure to air pollutants

K Hiraiwa, SF van Eeden - Mediators of inflammation, 2013 - Wiley Online Library
Large population cohort studies have indicated an association between exposure to
particulate matter and cardiopulmonary morbidity and mortality. The inhalation of toxic …

Systemic inflammatory response induced by particulate matter air pollution: the importance of bone-marrow stimulation

SF Eeden, JC Hogg - … of Toxicology and Environmental Health, Part …, 2002 - Taylor & Francis
The relationship between the level of particulate air pollution (PM 10) and the mortality and
morbidity rates from respiratory and cardiovascular diseases is well established, but the …

Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms

GRS Budinger, JL McKell, D Urich, N Foiles, I Weiss… - PloS one, 2011 - journals.plos.org
Background Exposure of human populations to ambient particulate matter (PM) air pollution
significantly contributes to the mortality attributable to ischemic cardiovascular events. We …

Cytokines Involved in the Systemic Inflammatory Response Induced by Exposure to Particulate Matter Air Pollutants (PM10)

SF van EEDEN, WC Tan, T Suwa, H Mukae… - American journal of …, 2001 - atsjournals.org
Elevated levels of ambient particulate matter (PM10) have been associated with increased
cardiopulmonary morbidity and mortality. We previously showed that the deposition of …

Pulmonary particulate matter and systemic microvascular dysfunction.

TR Nurkiewicz, DW Porter, AF Hubbs… - … report (Health Effects …, 2011 - europepmc.org
Pulmonary particulate matter (PM) exposure has been epidemiologically associated with an
increased risk of cardiovascular morbidity and mortality, but the mechanistic foundations for …