Evaluation on biological compatibility of carboxymethyl chitosan as biomaterials for antitumor drug delivery

Z Jiang, B Han, W Liu, Y Peng - Journal of Biomaterials …, 2017 - journals.sagepub.com
Carboxymethyl-chitosan, a water-soluble derivative of chitosan, has emerged as a
promising candidate for biomedical applications due to its excellent water solubility …

Synthesis, characterization and biological safety of O-carboxymethyl chitosan used to treat Sarcoma 180 tumor

M Zheng, B Han, Y Yang, W Liu - Carbohydrate Polymers, 2011 - Elsevier
Carboxymethyl chitosan (CM-chitosan) was prepared and characterized by FTIR and NMR
spectroscopy, and its biological safety in tumor application was investigated both in vitro and …

Preparation and anti-tumor metastasis of carboxymethyl chitosan

Z Jiang, B Han, H Li, X Li, Y Yang, W Liu - Carbohydrate polymers, 2015 - Elsevier
Carboxymethyl chitosan (CMCS), one of the most important water soluble chitosan
derivatives, has great potentials in biomedical applications due to its excellent water …

Anticancer properties of chitosan on human melanoma are cell line dependent

L Gibot, S Chabaud, S Bouhout, S Bolduc… - International journal of …, 2015 - Elsevier
Purpose Chitosan, a natural macromolecule, is widely used in medical and pharmaceutical
fields because of its distinctive properties such as bactericide, fungicide and above all its …

Multifaceted applications of chitosan in cancer drug delivery and therapy

A Babu, R Ramesh - Marine drugs, 2017 - mdpi.com
Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and
biodegradable nature of chitosan, it is intensively utilized in biomedical applications in …

Fabrication and characterization of unique sustain modified chitosan nanoparticles for biomedical applications

MES Ahmed, MI Mohamed, HY Ahmed… - Scientific Reports, 2024 - nature.com
Chitosan (CS) is a biopolymer that offers a wide range in biomedical applications due to its
biocompatibility, biodegradability, low toxicity and antimicrobial activity. Syringaldehyde (1) …

Synthesis and characterization of chitosan-based biomaterials modified with different active groups and their relationship with cytotoxicity

Y Lv, X Chen, Q Wang, Y Wang, J Zhang, C Liu… - Journal of Wuhan …, 2007 - Springer
The cytotoxicity profile of three chitosan derivatives with different affinity to water was
evaluated in vitro. The derivatives selected were carboxymethylated-chitosan (CMCH) …

Using chitosan or chitosan derivatives in cancer therapy

MS Shakil, KM Mahmud, M Sayem, MS Niloy… - Polysaccharides, 2021 - mdpi.com
Cancer is one of the major causes of death worldwide. Chemotherapeutic drugs have
become a popular choice as anticancer agents. Despite the therapeutic benefits of …

Chitosan modified by organo-functionalities as an efficient nanoplatform for anti-cancer drug delivery process

S Jaiswal, PK Dutta, S Kumar, R Chawla - Journal of Drug Delivery Science …, 2021 - Elsevier
Cancer, one of the lethal threats to human health, is most frequently treated with surgery,
chemotherapy and radiation. Specific receptors and abnormal physiochemical conditions …

Synthesis, biodegradability and cytotoxicity of water-soluble isobutylchitosan

DH Li, LM Liu, KL Tian, JC Liu, XQ Fan - Carbohydrate polymers, 2007 - Elsevier
The objective of the present study was to improve the solubility of chitosan at neutral
aqueous solution without altering its bioactivity. Through an alkylation reaction under mild …