A generalized procedure for calibrated MRI incorporating hyperoxia and hypercapnia
CJ Gauthier, RD Hoge - Human brain mapping, 2013 - Wiley Online Library
Calibrated MRI techniques use the changes in cerebral blood flow (CBF) and blood
oxygenation level‐dependent (BOLD) signal evoked by a respiratory manipulation to …
oxygenation level‐dependent (BOLD) signal evoked by a respiratory manipulation to …
Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model
RD Hoge, J Atkinson, B Gill, GR Crelier… - … in Medicine: An …, 1999 - Wiley Online Library
The relationship between blood oxygenation level‐dependent (BOLD) MRI signals, cerebral
blood flow (CBF), and oxygen consumption (CMRO2) in the physiological steady state was …
blood flow (CBF), and oxygen consumption (CMRO2) in the physiological steady state was …
Magnetic resonance imaging of resting OEF and CMRO2 using a generalized calibration model for hypercapnia and hyperoxia
CJ Gauthier, RD Hoge - Neuroimage, 2012 - Elsevier
We present a method allowing determination of resting cerebral oxygen metabolism
(CMRO2) from MRI and end-tidal O2 measurements acquired during a pair of respiratory …
(CMRO2) from MRI and end-tidal O2 measurements acquired during a pair of respiratory …
Measurement of OEF and absolute CMRO2: MRI-based methods using interleaved and combined hypercapnia and hyperoxia
Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI)
is most commonly used in a semi-quantitative manner to infer changes in brain activity …
is most commonly used in a semi-quantitative manner to infer changes in brain activity …
Calibrated functional MRI: mapping the dynamics of oxidative metabolism
TL Davis, KK Kwong, RM Weisskoff… - Proceedings of the …, 1998 - National Acad Sciences
MRI was extended to the measurement of changes in oxidative metabolism in the normal
human during functionally induced changes in cellular activity. A noninvasive MRI method …
human during functionally induced changes in cellular activity. A noninvasive MRI method …
[HTML][HTML] Measurement of oxygen extraction fraction (OEF): An optimized BOLD signal model for use with hypercapnic and hyperoxic calibration
A Merola, K Murphy, AJ Stone, MA Germuska… - Neuroimage, 2016 - Elsevier
Several techniques have been proposed to estimate relative changes in cerebral metabolic
rate of oxygen consumption (CMRO 2) by exploiting combined BOLD fMRI and cerebral …
rate of oxygen consumption (CMRO 2) by exploiting combined BOLD fMRI and cerebral …
MRI measurement of oxygen extraction fraction, mean vessel size and cerebral blood volume using serial hyperoxia and hypercapnia
M Germuska, DP Bulte - Neuroimage, 2014 - Elsevier
Functional magnetic resonance imaging measures signal increases arising from a variety of
interrelated effects and physiological sources. Recently there has been some success in …
interrelated effects and physiological sources. Recently there has been some success in …
A calibration method for quantitative BOLD fMRI based on hyperoxia
The estimation of changes in CMRO2 using functional MRI involves an essential calibration
step using a vasoactive agent to induce an isometabolic change in CBF. This calibration …
step using a vasoactive agent to induce an isometabolic change in CBF. This calibration …
Calibrated fMRI
RD Hoge - Neuroimage, 2012 - Elsevier
Functional magnetic resonance imaging with blood oxygenation level-dependent (BOLD)
contrast has had a tremendous influence on human neuroscience in the last twenty years …
contrast has had a tremendous influence on human neuroscience in the last twenty years …
[HTML][HTML] Sources of systematic error in calibrated BOLD based mapping of baseline oxygen extraction fraction
Recently a new class of calibrated blood oxygen level dependent (BOLD) functional
magnetic resonance imaging (MRI) methods were introduced to quantitatively measure the …
magnetic resonance imaging (MRI) methods were introduced to quantitatively measure the …