The recent advent of the Clustered Regularly Interspaced Short Palindromic Repeats
(CRISPR)‐CRISPR associated protein 9 (Cas9) system for precise genome editing has …

Summary The Clustered Regularly Interspaced Short Palindromic Repeats
(CRISPR)/CRISPR‐associated (Cas) 9 platform offers an efficient way of making precise …

The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has
revolutionized the gene editing field, making it possible to interrupt, insert or replace a …

Advances in genome engineering in the last decade, particularly in the development of
programmable nucleases, have made it possible to edit the genomes of most cell types …

Highlights•Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 is a
powerful tool for genome editing in hematopoietic cells, including primary hematopoietic …

The clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9
(CRISPR/Cas9) system is a versatile and convenient genome-editing tool with prospects in …

Genome editing therapies represent a significant advancement in next‐generation,
precision medicine for the management of haematological diseases, and CRISPR/Cas9 has …

The progress of genetic engineering in the 1970s brought about a paradigm shift in genome
editing technology. The clustered regularly interspaced short palindromic repeats/CRISPR …

Gene therapy represents a significant potential to revolutionize the field of hematology with
applications in correcting genetic mutations, generating cell lines and animal models, and …

Highlights•CRISPR/Cas9 overcomes limitations of earlier targeted nuclease-mediated
methods.•CRISPR/Cas9 allows for insertions/deletions of multiple alleles in a single …