The PA0336 protein from Pseudomonas aeruginosa belongs to the family of widely
distributed Nudix pyrophosphohydrolases, which catalyze the hydrolysis of pyrophosphate …

Post-transcriptional regulation enables bacteria to quickly response to environmental
stresses. Polynucleotide phosphorylase (PNPase), which contains an N-terminal catalytic …

Pseudomonas aeruginosa employs numerous, complex regulatory elements to control
expression of its many virulence systems. The P. aeruginosa AlgZR two-component …

Background: RppH initiates mRNA degradation in bacteria by removing pyrophosphate from
the triphosphorylated 5′ terminus. Results: X-ray structures of E. coli RppH have revealed …

Nudix proteins catalyze the hydrolysis of pyrophosphate bonds in a variety of substrates and
are ubiquitous in all domains of life. The genome of an important opportunistic human …

Small non-coding RNAs (sRNAs) are post-transcriptional regulators of gene expression that
have been recognized as key contributors to bacterial virulence and pathogenic …

Pseudomonas aeruginosa is capable of causing acute and chronic infections in various host
tissues, which depends on its abilities to effectively utilize host-derived nutrients and …

Pyocyanin, a main virulence factor that is produced by Pseudomonas aeruginosa, plays an
important role in pathogen-host interaction during infection. Two copies of phenazine …

The opportunistic pathogen P seudomonas aeruginosa PAO1 has a remarkable capacity to
adapt to various environments and to survive with limited nutrients. Here, we report the …

Pyocyanin, an important virulence factor, is synthesized and secreted by Pseudomonas
aeruginosa PAO1and plays a critical role in pathogen-host interaction during infection …