Endoribonuclease YbeY is essential for RNA processing and virulence in Pseudomonas aeruginosa

Y Xia, Y Weng, C Xu, D Wang, X Pan, Z Tian, B Xia… - MBio, 2020 - Am Soc Microbiol
Posttranscriptional regulation plays an essential role in the quick adaptation of pathogenic
bacteria to host environments, and RNases play key roles in this process by modifying small …

Systematic Mutational Analysis of the Putative Hydrolase PqsE: Toward a Deeper Molecular Understanding of Virulence Acquisition in Pseudomonas aeruginosa

B Folch, E Déziel, N Doucet - PLoS One, 2013 - journals.plos.org
Pseudomonas aeruginosa is an important opportunistic human pathogen that can establish
bacterial communication by synchronizing the behavior of individual cells in a molecular …

NudC Nudix hydrolase from Pseudomonas syringae, but not its counterpart from Pseudomonas aeruginosa, is a novel regulator of intracellular redox balance …

M Modzelan, M Kujawa, K Głąbski… - Molecular …, 2014 - Wiley Online Library
Nudix pyrophosphatases, ubiquitous in all organisms, have not been well studied. Recent
implications that some of them may be involved in response to stress and in pathogenesis …

Pseudomonas aeruginosa Polynucleotide Phosphorylase Contributes to Ciprofloxacin Resistance by Regulating PrtR

Z Fan, H Chen, M Li, X Pan, W Fu, H Ren… - Frontiers in …, 2019 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic bacterial pathogen that causes various acute
and chronic infections. It is intrinsically resistant to a variety of antibiotics. However …

PA2146 Gene Knockout Is Associated With Pseudomonas aeruginosa Pathogenicity in Macrophage and Host Immune Response

P She, Y Liu, Z Luo, L Chen, L Zhou… - Frontiers in Cellular …, 2020 - frontiersin.org
Pseudomonas aeruginosa is a common gram-negative bacterium that usually causes
nosocomial infection. The main pathogenicity of P. aeruginosa is caused by its virulence …

Pseudomonas aeruginosa regulator PvrA binds simultaneously to multiple pseudo-palindromic sites for efficient transcription activation

Y Zhu, B Luo, X Mou, Y Song, Y Zhou, Y Luo… - Science China Life …, 2024 - Springer
Tetracycline repressor (TetR) family regulators (TFRs) are the largest group of DNA-binding
transcription factors and are widely distributed in bacteria and archaea. TFRs play vital roles …

[HTML][HTML] DNA alternate polymerase PolB mediates inhibition of type III secretion in Pseudomonas aeruginosa

S Chakravarty, L Ramos-Hegazy, A Gasparovic… - Microbes and …, 2021 - Elsevier
Opportunistic pathogen Pseudomonas aeruginosa uses a variety of virulence factors to
cause acute and chronic infections. We previously found that alternate DNA polymerase …

Structure and biological function of the RNA pyrophosphohydrolase BdRppH from Bdellovibrio bacteriovorus

SAJ Messing, SB Gabelli, Q Liu, H Celesnik… - Structure, 2009 - cell.com
Until recently, the mechanism of mRNA decay in bacteria was thought to be different from
that of eukaryotes. This paradigm changed with the discovery that RppH …

PmtA Regulates Pyocyanin Expression and Biofilm Formation in Pseudomonas aeruginosa

AV Thees, KM Pietrosimone, CK Melchiorre… - Frontiers in …, 2021 - frontiersin.org
The opportunistic pathogen Pseudomonas aeruginosa expresses a small molecular weight,
cysteine-rich protein (PmtA), identified as a metallothionein (MT) protein family member. The …

A UDP-X Diphosphatase from Streptococcus pneumoniae Hydrolyzes Precursors of Peptidoglycan Biosynthesis

KC Duong-Ly, HN Woo, CA Dunn, WL Xu, A Babič… - PloS one, 2013 - journals.plos.org
The gene for a Nudix enzyme (SP_1669) was found to code for a UDP-X diphosphatase.
The SP_1669 gene is localized among genes encoding proteins that participate in cell …