The incidence of cardiovascular diseases was significantly increased in postmenopausal
women. The protection of estrogen in the cardiovascular system has been further reported …

The incidence of heart failure mainly resulting from cardiac hypertrophy and fibrosis
increases sharply in post-menopausal women compared with men at the same age, which …

Aims Estrogen plays an important role in cardioprotection. Animal experiments showed that
the G-protein coupled estrogen receptor 30 (GPR30) specific agonist G1 could reduce post …

Background G-protein-coupled ER (GPR30) plays an important role in cardioprotection.
Recent studies have shown that the GPR30-specific agonist G-1 reduces the degree of …

Estrogen has been demonstrated to protect the heart against cardiac remodelling and heart
failure in women. G protein-coupled estrogen receptor 1 (GPER1) is a recently discovered …

The incidence of left ventricular diastolic dysfunction significantly increases in
postmenopausal women suggesting the association between estrogen loss and diastolic …

Estrogen receptors, including classic nuclear receptors ERα, ERβ, and membrane receptor
GPR30, are expressed in vascular tissues and exert protective actions in vascular diseases …

Premenopausal females have a comparably lower incidence of cardiovascular disease than
their male counterparts. Although estrogen and activation of estrogen receptors (ERs) have …

Aims GPR30 is a novel oestrogen receptor expressed in various tissues, including the heart.
We determined the role of GPR30 in the maintenance of left ventricular (LV) structure and …

Premenopausal women have a reduced risk for cardiovascular disease. Estrogen deficiency
augments cardiac inflammation and oxidative stress and, thereby, aggravates myocardial …