(Headache 2011; 51: 880‐890) Migraine is an episodic brain disorder that is characterized
by recurrent attacks of severe unilateral headache that are accompanied by various …

Background Receptor activity modifying protein 1 (RAMP1) is a key receptor subunit of
calcitonin gene related peptide (CGRP) playing a critical role in migraine. But variations in …

Migraine is a common, disabling, and undertreated episodic brain disorder that is more
common in women than in men. Unbiased genome-wide association studies have identified …

Epilepsy and migraine often co-occur. From the clinical symptoms, they often have some
signs of symptoms before onset; from the pathogenesis of epilepsy and migraine, both of …

Pediatric migraine is a disabling condition that can affect the everyday activities and
emotional states of children. Due to the multifactorial character of the pathology and the …

The field of migraine genetics has seen an explosion of information over the last year. In a
recent breakthrough, missense mutations in a chromosome 1q23 gene, ATP1A2, encoding …

Background The transition from episodic migraine to chronic migraine, migraine
chronification, is usually a gradual process, which involves multiple risk factors. To date …

Although the exact cascade of events that culminate into a migraine attack remains elusive,
the mechanisms that underlie the manifestation of migraine pain have been better studied …

Migraine is a common multifactorial episodic brain disorder with strong genetic basis.
Monogenic subtypes include rare familial hemiplegic migraine, cerebral autosomal …

Published with the New York Academy of Sciences A timely, broad-ranging exploration of
the neurobiological basis and molecular mechanisms of migraines Migraines impact the …