A new malignancy was diagnosed in 19 of 414 long‐term survivors of cancer in childhood.
All but two lesions were attributable to prior radiotherapy; eight were successfully treated …

Studies were made of the development of second malignant tumors in children treated at the
Sidney Farber Cancer Institute. In 1973 a retrospective analysis identified second cancers in …

Review of hospital charts of 168 patients surviving two or more years following the diagnosis
of cancer and subsequent examinations of 40 of these patients yielded these …

Among a cohort of 9,279 survivors of childhood neoplasms other than retinoblastoma
treated in Britain before 1980, the cumulative risk of a second primary tumor (SPT) by 25 …

Many pediatric and adolescent cancer patients are treated with carcinogenic
chemotherapeutic agents and radiation therapy to achieve permanent control of their …

Purpose To determine the risk of subsequent carcinomas other than breast, thyroid, and
skin, and to identify factors that influence the risk among survivors of childhood cancer …

[en] The study of long-term effects of therapy for childhood cancer is important for several
reasons. An increasing proportion of children are now cured of their cancer and can expect …

As more children are now being cured of cancer, increasing attention needs to be focused
on the long‐term sequelae of cancer therapy, principally late‐appearing second cancers …

As the population of cancer survivors has increased and continues to age, the occurrence of
second cancers has risen dramatically-from 9% of all cancer diagnoses in 1975-1979 to …

Abstract purpose: Although most second malignancies are treatment related, their
occurrence also may be due to an underlying systemic disease or chromosomal …