Twelve clinical and 102 fecal isolates from healthy carriers of Clostridium perfringens type A
were tested for virulence in juvenile, outbred NMRI mice (intramuscular route). There were …

Penicillin G and imipenem (N-formimidoyl thienamycin) in vitro were the most active of
twelve examined antimicrobial drugs against clinical and fecal isolates of Clostridium …

Four Clostridium perfringens strains recovered from clinical specimens, four strains obtained
from faecal specimens of healthy adults, and control strain ATCC 13124 were inoculated …

Clostridium perfringens type D isolates cause enterotoxemia in sheep, goats, and probably
cattle. While the major disease signs and lesions of type D animal disease are usually …

Ischemic and hemorrhagic strangulation of closed intestinal segments was studied in germ-
free rats individually contaminated with one of seven separate strains of Clostridium …

Axenic mice died with signs of enterotoxaemia after oral ingestion ofClostridium perfringens
type C or D. Under the same conditions, C. perfringens type B was less pathogenic, and …

The most common animal models used to study Clostridium perfringens infections in
humans and animals are reviewed here. The classical C. perfringens-mediated histotoxic …

Germ-free guinea pigs died with signs and lesions of acute enterotoxemia after oral
ingestion of C. perfringens types B, C, D, and E. The signs and lesions observed resembled …

We have recently reported (DL Stevens, KA Maier, BM Laine, and JE Mitten, J. Infect. Dis.
155: 220-228, 1987) that clindamycin, rifampin, and tetracycline were more efficacious than …

Clostridium perfringens has been described as the most important anaerobic pathogen of
man, and is considered the most common cause of enteric diseases in animals. Virulency of …