The P2Y12 receptor expressed in satellite cells of the trigeminal ganglion is thought to
contribute to neuropathic pain. The functional interaction between neurons and satellite cells …

We reported earlier that TNF-a, a proinflammatory cytokine implicated in many inflammatory
disorders causing orofacial pain, increases the activity of Cdk5, a key kinase involved in …

Background: Microvascular compression of the trigeminal nerve root is a major cause of
most trigeminal neuralgia (TN) in patients; however, no reliable animal model to further …

Objective Elevated levels of tumor necrosis factor-alpha (TNF-α) in the capsule of the
temporomandibular joint (TMJ) are implicated in the underlying pathology of …

Background: It has been reported that the P2Y12 receptor (P2Y12R) is involved in satellite
glial cells (SGCs) activation, indicating that P2Y12R expressed in SGCs may play functional …

In order to investigate a putative role for nitric oxide (NO) in the central nociceptive
processing following carrageenan-induced arthritis in the rat temporomandibular joint (TMJ) …

We previously demonstrated that sodium channel 1.7 (Nav1. 7) in trigeminal ganglion (TG)
was a critical factor in temporomandibular joint (TMJ) inflammation-induced …

Background The trigeminal subnuclei interpolaris/caudalis transition zones (Vi/Vc) play an
important role in orofacial deep pain, however, the role of primary afferent projections to the …

Temporomandibular disorders represent one of the major challenges in dentistry
therapeutics. This study was undertaken to evaluate the time course of carrageenan …

Neuroplastic changes in the neuronal networks involving the trigeminal ganglion (TG),
trigeminal spinal subnucleus caudalis (Vc), and upper cervical spinal cord (C1/C2) are …