Impact of the nanoparticle–protein corona on colloidal stability and protein structure
JS Gebauer, M Malissek, S Simon, SK Knauer… - Langmuir, 2012 - ACS Publications
In biological fluids, proteins may associate with nanoparticles (NPs), leading to the formation
of a so-called “protein corona” largely defining the biological identity of the particle. Here, we …
of a so-called “protein corona” largely defining the biological identity of the particle. Here, we …
An analysis of the binding function and structural organization of the protein corona
Blood proteins adsorb onto the surface of nanoparticles after intravenous injection to form a
protein corona. The underlying organization and binding function of these adsorbed proteins …
protein corona. The underlying organization and binding function of these adsorbed proteins …
Biomolecular coronas provide the biological identity of nanosized materials
Fundamentally, all interactions between the nanoparticle corona complex and the biological
machinery are mediated by physical forces common to all molecular systems. The …
machinery are mediated by physical forces common to all molecular systems. The …
Reversible versus Irreversible Binding of Transferrin to Polystyrene Nanoparticles: Soft and Hard Corona
S Milani, F Baldelli Bombelli, AS Pitek, KA Dawson… - ACS …, 2012 - ACS Publications
Protein adsorption to nanoparticles (NPs) is a key prerequisite to understand NP–cell
interactions. While the layer thickness of the protein corona has been well characterized in …
interactions. While the layer thickness of the protein corona has been well characterized in …
Protein corona in response to flow: effect on protein concentration and structure
Nanoparticles used in cellular applications encounter free serum proteins that adsorb onto
the surface of the nanoparticle, forming a protein corona. This protein layer controls the …
the surface of the nanoparticle, forming a protein corona. This protein layer controls the …
Measurements of heterogeneity in proteomics analysis of the nanoparticle protein corona across core facilities
Robust characterization of the protein corona—the layer of proteins that spontaneously
forms on the surface of nanoparticles immersed in biological fluids—is vital for prediction of …
forms on the surface of nanoparticles immersed in biological fluids—is vital for prediction of …
In Situ Analysis of Weakly Bound Proteins Reveals Molecular Basis of Soft Corona Formation
D Sanchez-Guzman, G Giraudon--Colas, L Marichal… - ACS …, 2020 - ACS Publications
Few experimental techniques allow the analysis of the protein corona in situ. As a result,
little is known on the effects of nanoparticles on weakly bound proteins that form the soft …
little is known on the effects of nanoparticles on weakly bound proteins that form the soft …
Evolution of the nanoparticle corona
M Hadjidemetriou, K Kostarelos - Nature nanotechnology, 2017 - nature.com
Evolution of the nanoparticle corona | Nature Nanotechnology Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To …
for visiting nature.com. You are using a browser version with limited support for CSS. To …
Studying the protein corona on nanoparticles by FCS
GU Nienhaus, P Maffre, K Nienhaus - Methods in enzymology, 2013 - Elsevier
Engineered nanoparticles (NPs) have found widespread application in technology and
medicine. Whenever they come in contact with a living organism, interactions take place …
medicine. Whenever they come in contact with a living organism, interactions take place …
The effect of surface nanometre-scale morphology on protein adsorption
PE Scopelliti, A Borgonovo, M Indrieri, L Giorgetti… - PloS one, 2010 - journals.plos.org
Background Protein adsorption is the first of a complex series of events that regulates many
phenomena at the nano-bio interface, eg cell adhesion and differentiation, in vivo …
phenomena at the nano-bio interface, eg cell adhesion and differentiation, in vivo …