The crown and the scepter: roles of the protein corona in nanomedicine
Engineering nanomaterials are increasingly considered promising and powerful biomedical
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …
Environmental dimensions of the protein corona
The adsorption of biomolecules to the surface of engineered nanomaterials, known as
corona formation, defines their biological identity by altering their surface properties and …
corona formation, defines their biological identity by altering their surface properties and …
Understanding the nanoparticle–protein corona complexes using computational and experimental methods
Nanoparticles (NP) have capability to adsorb proteins from biological fluids and form protein
layer, which is called protein corona. As the cell sees corona coated NPs, the protein corona …
layer, which is called protein corona. As the cell sees corona coated NPs, the protein corona …
Role of protein corona in the biological effect of nanomaterials: Investigating methods
L Zeng, J Gao, Y Liu, J Gao, L Yao, X Yang… - TrAC Trends in …, 2019 - Elsevier
Growing developments in engineered nanomaterials (NMs) and their wide applications
inevitably raise environmental and human health concerns. Upon contact with biological …
inevitably raise environmental and human health concerns. Upon contact with biological …
Physical−Chemical Aspects of Protein Corona: Relevance to in Vitro and in Vivo Biological Impacts of Nanoparticles
MP Monopoli, D Walczyk, A Campbell… - Journal of the …, 2011 - ACS Publications
It is now clearly emerging that besides size and shape, the other primary defining element of
nanoscale objects in biological media is their long-lived protein (“hard”) corona. This corona …
nanoscale objects in biological media is their long-lived protein (“hard”) corona. This corona …
Nanoparticle protein corona: from structure and function to therapeutic targeting
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …
However, despite the clinical success of NP technology, it is not well-understood how NPs …
Visualization of the protein corona: towards a biomolecular understanding of nanoparticle-cell-interactions
M Kokkinopoulou, J Simon, K Landfester, V Mailänder… - Nanoscale, 2017 - pubs.rsc.org
The use of nanocarriers in biology and medicine is complicated by the current need to
understand how nanoparticles interact in complex biological surroundings. When …
understand how nanoparticles interact in complex biological surroundings. When …
Quantitative profiling of the protein coronas that form around nanoparticles
D Docter, U Distler, W Storck, J Kuharev, D Wünsch… - Nature protocols, 2014 - nature.com
Nanoparticle applications in biotechnology and biomedicine are steadily increasing. In
biological fluids, proteins bind to nanoparticles that form the protein corona, crucially …
biological fluids, proteins bind to nanoparticles that form the protein corona, crucially …
Influence of surface chemistry and morphology of nanoparticles on protein corona formation
R Bilardo, F Traldi, A Vdovchenko… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Nanomaterials offer promising solutions as drug delivery systems and imaging agents in
response to the demand for better therapeutics and diagnostics. However, the limited …
response to the demand for better therapeutics and diagnostics. However, the limited …
Interplay between nanomedicine and protein corona
M Yang, E Wu, W Tang, J Qian, C Zhan - Journal of Materials …, 2021 - pubs.rsc.org
Nanomedicine is recognized as a promising agent for diverse biomedical applications;
however, its safety and efficiency in clinical practice remains to be enhanced. A priority issue …
however, its safety and efficiency in clinical practice remains to be enhanced. A priority issue …