Flutamide is a nonsteroidal pure antiandrogen that acts by inhibiting the uptake and/or
binding of dihydrotestosterone to the target cell receptor, thus interfering with androgen …

Synopsis Flutamide is a non-steroidal antiandrogenic drug devoid of hormonal agonist
activity. Flutamide appears to be a specific antiandrogen only at androgen-dependent …

Synopsis Flutamide, a nonsteroidal antiandrogenic drug devoid of hormonal agonist activity,
is used in the treatment of advanced prostate cancer. In previously untreated patients …

Objective: In a multicenter study, 905 patients with newly diagnosed advanced prostate
cancer treated with flutamide were followed for safety and side effects. Methods: Flutamide …

In a recent intergroup study under the auspices of the National Cancer Institute, 603 eligible
patients with newly diagnosed disseminated adenocarcinoma of the prostate were …

Backgroound The best treatment for patients with “hormone-refractory” metastatic prostate
cancer is unclear, particularly in patients for whom suramin and hydrocortisone have failed …

Abstract Flutamide (250 mg. orally 3 times daily) yielded a subjective response in 5 of 25
fully evaluable patients with hormone-resistant prostatic cancer. Four additional patients had …

Little is known about the efficacy of flutamide monotherapy in previously untreated patients
with prostatic carcinoma. In this study, 40 patients with advanced disease were treated with …

Flutamide is a nonsteroidal antiandrogen used in the treatment of prostatic carcinoma. We
have investigated the disposition of flutamide and its two major metabolites in ten urological …

Purpose: To compare in a randomized clinical trial the therapeutic efficacy of the
nonsteroidal antiandrogen flutamide 250 mg tid to testicular androgen suppression by …