[HTML][HTML] Sulfasalazine-loaded nanoparticles for efficient inflammatory bowel disease therapy via ROS-scavenging strategy
S Lin, H Zhao, C Xu, P Zhang, X Mei, D Jiang - Materials & Design, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a life-threatening organ dysfunction amplified by
complex interactions between genetic, environmental, and immune factors. Sulfasalazine …
complex interactions between genetic, environmental, and immune factors. Sulfasalazine …
A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease
F Zeng, Y Shi, C Wu, J Liang, Q Zhong, K Briley… - Journal of …, 2022 - Springer
Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …
Construction of pH‐Dependent Nanozymes with Oxygen Vacancies as the High‐Efficient Reactive Oxygen Species Scavenger for Oral‐Administrated Anti …
N Zhao, FE Yang, CY Zhao, SW Lv… - Advanced …, 2021 - Wiley Online Library
It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
Zero‐valence selenium‐enriched Prussian blue nanozymes reconstruct intestinal barrier against inflammatory bowel disease via inhibiting Ferroptosis and T cells …
D Zhu, H Wu, K Jiang, Y Xu, Z Miao… - Advanced Healthcare …, 2023 - Wiley Online Library
The structural disruption of mechanical barrier and dysfunction of immune barrier in
intestinal, are important factors, that aggravate inflammatory bowel disease (IBD). To tackle …
intestinal, are important factors, that aggravate inflammatory bowel disease (IBD). To tackle …
Cyclosporine A-encapsulated pH/ROS dual-responsive nanoformulations for the targeted treatment of colitis in mice
S Li, T Wu, J Wu, J Zhou, H Yang, L Chen… - ACS Biomaterials …, 2023 - ACS Publications
Inflammatory bowel disease (IBD) is a frequently occurring disease that seriously influences
the patient's quality of life. To decrease adverse effects and improve efficacy of therapeutics …
the patient's quality of life. To decrease adverse effects and improve efficacy of therapeutics …
ROS responsive polydopamine nanoparticles to relieve oxidative stress and inflammation for ameliorating acute inflammatory bowel
M Yan, L Zhu, S Wu, Y Cao, N Mou, Q Chi, G Wang… - Biomaterials …, 2022 - Elsevier
Oxidative stress is a key factor in the development of inflammatory diseases. Elimination of
reactive oxygen species (ROS) in the inflamed colon has been confirmed as an effective …
reactive oxygen species (ROS) in the inflamed colon has been confirmed as an effective …
Ultrasmall Cu2O@His Nanozymes with RONS Scavenging Capability for Anti-inflammatory Therapy
S Li, Z Chen, M Wang, F Yang, S Zhang… - … Applied Materials & …, 2024 - ACS Publications
High concentrations of reactive oxygen and nitrogen species (RONS) are key characteristics
of inflammatory sites. Scavenging RONS at the site of inflammation is an effective …
of inflammatory sites. Scavenging RONS at the site of inflammation is an effective …
ROS Scavenging and inflammation-directed polydopamine nanoparticles regulate gut immunity and flora therapy in inflammatory bowel disease
M Bao, K Wang, J Li, Y Li, H Zhu, M Lu, Y Zhang… - Acta Biomaterialia, 2023 - Elsevier
Dysfunction of the intestinal mucosal immune system and dysbiosis of the intestinal
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …
Readily Available Oral Prebiotic Protein Reactive Oxygen Species Nanoscavengers for Synergistic Therapy of Inflammation and Fibrosis in Inflammatory Bowel …
Y Yu, D Yang, B Lin, L Zhu, C Li, X Li - ACS nano, 2024 - ACS Publications
A significant gap exists in the demand for safe and effective drugs for inflammatory bowel
disease (IBD), and its associated intestinal fibrosis. As oxidative stress plays a central role in …
disease (IBD), and its associated intestinal fibrosis. As oxidative stress plays a central role in …
Nanoparticles derived from the natural antioxidant rosmarinic acid ameliorate acute inflammatory bowel disease
Rosmarinic acid (RA), one of the most important polyphenol-based antioxidants, has
received growing interest because of its bioactive properties, including anti-inflammatory …
received growing interest because of its bioactive properties, including anti-inflammatory …
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