Duration of diabetes and cardiorenal efficacy of liraglutide and semaglutide: A post hoc analysis of the LEADER and SUSTAIN 6 clinical trials

S Verma, SC Bain, T Monk Fries… - Diabetes, Obesity …, 2019 - Wiley Online Library
Cardiovascular risk reduction with liraglutide and semaglutide in patients with type 2
diabetes was demonstrated in the LEADER (ClinicalTrials. gov: NCT01179048) and …

Effects of glucagon‐like peptide‐1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across body mass index categories in type 2 …

S Verma, DK McGuire, SC Bain… - Diabetes, Obesity …, 2020 - Wiley Online Library
Associations between body mass index (BMI) and the cardiovascular (CV) and kidney
efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in patients with type 2 …

The effect of glucagon‐like peptide‐1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across baseline blood pressure categories …

LA Leiter, SC Bain, DL Bhatt, JB Buse… - Diabetes, Obesity …, 2020 - Wiley Online Library
It is unknown if the cardioprotective and renal effects of glucagon‐like peptide‐1 receptor
agonists are consistent across blood pressure (BP) categories in patients with type 2 …

Effects of liraglutide versus placebo on cardiovascular events in patients with type 2 diabetes mellitus and chronic kidney disease: results from the LEADER trial

JFE Mann, V Fonseca, O Mosenzon, I Raz… - Circulation, 2018 - Am Heart Assoc
Background: LEADER trial (Liraglutide Effect and Action in Diabetes: Evaluation of CV
Outcome Results) results demonstrated cardiovascular benefits for patients with type 2 …

Liraglutide and cardiovascular outcomes in a real world type 2 diabetes cohort

M Mirani, G Favacchio, E Serone, G Lucisano… - Pharmacological …, 2018 - Elsevier
In the last years, due to new regulatory guidelines requiring a stringent documentation of
cardiovascular (CV) safety of novel drugs for type 2 diabetes, cardiovascular outcomes …

[HTML][HTML] A significant effect of oral semaglutide on cardiovascular risk factors in patients with type 2 diabetes

H Yanai, M Hakoshima, H Adachi… - Cardiology …, 2022 - ncbi.nlm.nih.gov
Background The once-daily glucagon-like peptide 1 (GLP-1) analogue, liraglutide has been
shown to reduce major adverse cardiovascular events (MACE) and progression of chronic …

Cardiovascular efficacy of liraglutide and semaglutide in individuals with diabetes and peripheral artery disease

S Verma, M Al‐Omran, LA Leiter… - Diabetes, Obesity …, 2022 - Wiley Online Library
Aim To evaluate the cardiovascular (CV) efficacy of liraglutide and semaglutide in patients
with type 2 diabetes (T2D) and peripheral artery disease (PAD). Materials and Methods …

Effect of the glucagon-like peptide-1 receptor agonists semaglutide and liraglutide on kidney outcomes in patients with type 2 diabetes: pooled analysis of SUSTAIN 6 …

AM Shaman, SC Bain, GL Bakris, JB Buse, T Idorn… - Circulation, 2022 - Am Heart Assoc
Background: We assessed the effect of once-weekly semaglutide and once-daily liraglutide
on kidney outcomes in type 2 diabetes. Methods: Pooled (n= 12 637) and by-trial data from …

Cardiovascular risk reduction with liraglutide: an exploratory mediation analysis of the LEADER trial

JB Buse, SC Bain, JFE Mann, MA Nauck… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE The Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular
Outcome Results (LEADER) trial (ClinicalTrials. gov reg. no. NCT01179048) demonstrated a …

Cardiovascular effects of liraglutide

N Mikhail - Current Hypertension Reviews, 2019 - ingentaconnect.com
Background: Liraglutide is a glucagon-like 1 (GLP-1) agonist approved for treatment of type
2 diabetes and obesity. Objective: To review the cardiovascular effects of liraglutide …