The bile acid conjugate tauroursodeoxycholic acid (TUDCA) is a neuroprotective agent in
various animal models of neuropathologies. We have previously shown the anti …

Background Bile acids are steroid acids found predominantly in the bile of mammals. The
bile acid conjugate tauroursodeoxycholic acid (TUDCA) is a neuroprotective agent in …

Bile acids are steroid acids found in the bile of mammals. The bile acid conjugate
tauroursodeoxycholic acid (TUDCA) is neuroprotective in different animal models of stroke …

Neurological diseases are usually accompanied by dramatic changes in the tissue
homeostasis, inducing a neuroinflammatory environment that leads to the progressive …

Accumulating evidence has shown that tauroursodeoxycholic acid (TUDCA) is
neuroprotective in different animal models of neurological diseases. However, whether …

Traumatic brain injury (TBI) is one of the leading causes of trauma-induced mortality and
disability, and emerging studies have shown that endoplasmic reticulum (ER) stress plays …

Background Tauroursodeoxycholic acid (TUDCA) is a hydrophilic bile acid derivative, which
has been demonstrated to have neuroprotective effects in different neurological disease …

The objective of this review was to evaluate the potential of tauroursodeoxycholic acid
(TUDCA) for neuroprotection in traumatic brain injury (TBI) patients in the neurocritical care …

Background The over-expression of transforming growth factor β-1 (TGF-β1) has been
reported to cause hydrocephalus, glia activation, and vascular amyloidβ (Aβ) deposition in …

Depression is a mental disease that causes severe economic and social burdens. The
mechanism for the onset of depression remains largely unknown. Recently, more and more …