Chronic obstructive pulmonary disease (COPD) is characterized by alveolar destruction and
abnormal inflammatory responses to noxious stimuli. Surfactant protein–D (SFTPD) is …

Background and objective Although surfactant protein‐D (SP‐D) has been suggested as a
biomarker for chronic obstructive pulmonary disease (COPD), the relationship between …

Introduction: There are limited data linking serum levels of surfactant protein D, its genetic
polymorphisms to the risk of Chronic Obstructive Pulmonary Disease (COPD). Objectives …

Background: Surfactant protein D (SFTPD) is a lung specific protein which performs several
key regulatory processes to maintain overall lung function. Several infectious and immune …

Surfactant protein D (SP-D) is produced primarily in the lung and is involved in regulating
pulmonary surfactants, lipid homeostasis and innate immunity. Circulating SP-D levels in …

Variation in surfactant protein D (SP-D) is associated with lung function in tobacco smoke-
induced chronic respiratory disease. We hypothesized that the same association exists in …

Abstract Background and Objectives Chronic obstructive pulmonary disease (COPD) is a
complex chronic inflammatory disease that involves the activity of various inflammatory cells …

Background and objective A structural single nucleotide polymorphism rs721917 in the
surfactant protein D (SP‐D) gene, known as Met11Thr, was reported to influence the …

Surfactant protein D (SFTPD) induces emphysema in knockout mice, but the association of
SFTPD with chronic obstructive pulmonary disease (COPD) and emphysema in humans is …

Exacerbations of chronic obstructive pulmonary disease (COPD) reduce quality of life and
increase mortality. Genetic variation might explain the substantial variability seen in …