Decades of research have characterized diverse immune cells surveilling the CNS. More
recently, the discovery of osseous channels (so-called 'skull channels') connecting the …

It remains unclear how immune cells from skull bone marrow niches are recruited to the
meninges. Here we report that cerebrospinal fluid (CSF) accesses skull bone marrow via …

Innate immune cells recruited to inflammatory sites have short life spans and originate from
the marrow, which is distributed throughout the long and flat bones. While bone marrow …

INTRODUCTION Myeloid cells are highly heterogeneous, with distinct ontogenies and
immune functions. The diverse role of myeloid populations, including monocytes …

The bone marrow in the skull is important for shaping immune responses in the brain and
meninges, but its molecular makeup among bones and relevance in human diseases …

Discoveries leading to an improved understanding of immune surveillance of the central
nervous system (CNS) have repeatedly provoked dismissal of the existence of immune …

Whereas the study of the interactions between the immune system and the central nervous
system (CNS) has often focused on pathological conditions, the importance of neuroimmune …

Interactions between the immune and central nervous systems strongly influence brain
health. Although the blood–brain barrier restricts this crosstalk, we now know that meningeal …

The CNS is ensheathed by the meninges and cerebrospinal fluid, and recent findings
suggest that these CNS-associated border tissues have complex immunological functions …

Meningeal lymphatics near the cribriform plate undergo lymphangiogenesis during
neuroinflammation to drain excess fluid. Here, we hypothesized that lymphangiogenic …