Individual reports suggest that the central nervous system (CNS) contains multiple immune
cell types with diverse roles in tissue homeostasis, immune defense, and neurological …

Macrophages are important players in the maintenance of tissue homeostasis. Perivascular
and leptomeningeal macrophages reside near the central nervous system (CNS) …

The meninges are the fibrous covering of the central nervous system (CNS) which contain
vastly heterogeneous cell types within its three layers (dura, arachnoid, and pia). The dural …

Multiple Sclerosis (MS) is considered the most frequent inflammatory demyelinating disease
of the central nervous system (CNS). It occurs with a variable prevalence across the world. A …

The central nervous system is lined by meninges, classically known as dura, arachnoid, and
pia mater. We show the existence of a fourth meningeal layer that compartmentalizes the …

The central nervous system (CNS) coordinates all our body functions. Neurons in the CNS
parenchyma achieve this computational task by high speed communication via electrical …

Central nervous system (CNS) homeostasis is a prerequisite for the proper communication
of neuronal cells. To this end, the endothelial blood–brain barrier (BBB) and the epithelial …

Barriers between circulation and the central nervous system (CNS) play a key role in the
development and modulation of CNS immune responses. Structural variations in the …

Brain–immune cross-talk and neuroinflammation critically shape brain physiology in health
and disease. A detailed understanding of the brain immune landscape is essential for …

The meninges are often considered inert tissues that house the CSF and provide protection
for the brain and spinal cord. Yet emerging data demonstrates that they are also active sites …