[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The sudden emergence of severe respiratory disease, caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …

Genomic variations in the structural proteins of SARS-CoV-2 and their deleterious impact on pathogenesis: a comparative genomics approach

T Mohammad, A Choudhury, I Habib… - Frontiers in cellular …, 2021 - frontiersin.org
A continual rise in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection
causing coronavirus disease (COVID-19) has become a global threat. The main problem …

Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

Structural characterization of SARS-CoV-2: where we are, and where we need to be

G Mariano, RJ Farthing, SLM Lale-Farjat… - Frontiers in molecular …, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread in
humans in almost every country, causing the disease COVID-19. Since the start of the …

Potential drug targets of SARS-CoV-2: From genomics to therapeutics

A Shamsi, T Mohammad, S Anwar, S Amani… - International Journal of …, 2021 - Elsevier
The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) from
China has become a global threat due to the continuous rise in cases of Coronavirus …

The impact of structural bioinformatics tools and resources on SARS-CoV-2 research and therapeutic strategies

VP Waman, N Sen, M Varadi, A Daina… - Briefings in …, 2021 - academic.oup.com
SARS-CoV-2 is the causative agent of COVID-19, the ongoing global pandemic. It has
posed a worldwide challenge to human health as no effective treatment is currently …

SARS‐CoV‐2, the pandemic coronavirus: Molecular and structural insights

SB Kadam, GS Sukhramani, P Bishnoi… - Journal of basic …, 2021 - Wiley Online Library
The outbreak of a novel coronavirus associated with acute respiratory disease, called
COVID‐19, marked the introduction of the third spillover of an animal coronavirus (CoV) to …

COVID-19: A review of newly formed viral clades, pathophysiology, therapeutic strategies and current vaccination tasks

C Murugan, S Ramamoorthy, G Kuppuswamy… - International journal of …, 2021 - Elsevier
Today, the world population is facing an existential threat by an invisible enemy known as
severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) or COVID-19. It is highly …

Comparative genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in …

MI Khan, ZA Khan, MH Baig, I Ahmad, AEA Farouk… - PLoS …, 2020 - journals.plos.org
A novel severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) causing
COVID-19 pandemic in humans, recently emerged and has exported in more than 200 …

Morphology, genome organization, replication, and pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

S Kumar, R Nyodu, VK Maurya, SK Saxena - Coronavirus Disease 2019 …, 2020 - Springer
SARS-CoV-2 is a single-stranded RNA virus of~ 30 kb genome size which belongs to genus
Coronavirus and family Coronaviridae. SARS-CoV-2 has recently emerged and has been …