Modification of CEA with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC vaccination
SG Kim, MY Park, CH Kim, HJ Sohn, HS Kim, JS Park… - Vaccine, 2008 - Elsevier
Carcinoembryonic antigen (CEA) is expressed on human colon carcinomas, is well
characterized, and continues to be a promising target for cancer immunotherapy in humans …
characterized, and continues to be a promising target for cancer immunotherapy in humans …
Protective anti-tumour immune responses by murine dendritic cells pulsed with recombinant Tat-carcinoembryonic antigen derived from Escherichia coli
Carcinoembryonic antigen (CEA) is over-expressed on various human cancer cells and has
been the target of immunotherapies using dendritic cells (DCs) pulsed with CEA-specific …
been the target of immunotherapies using dendritic cells (DCs) pulsed with CEA-specific …
Co‐administration of carcinoembryonic antigen and HIV TAT fusion protein with CpG‐oligodeoxynucleotide induces potent antitumor immunity
SJ Woo, CH Kim, MY Park, HS Kim, HJ Sohn… - Cancer …, 2008 - Wiley Online Library
Although dendritic cells (DC) have been well demonstrated as a strong cellular adjuvant for
a tumor vaccine, there are several limitations for clinical application. A protein‐based …
a tumor vaccine, there are several limitations for clinical application. A protein‐based …
Efficient co-transduction of adenoviral vectors encoding carcinoembryonic antigen and survivin into dendritic cells by the CAR-TAT adaptor molecule enhance anti …
HS Kim, CH Kim, MY Park, JS Park, HM Park, HJ Sohn… - Immunology letters, 2010 - Elsevier
Because multiple tumor antigens, including carcinoembryonic antigen (CEA) and survivin
(SVV), have been frequently observed in human colorectal cancer, we investigated whether …
(SVV), have been frequently observed in human colorectal cancer, we investigated whether …
A loss of antitumor therapeutic activity of CEA DNA vaccines is associated with the lack of tumor cells' antigen presentation to Ag-specific CTLs in a colon cancer …
E Ahn, H Kim, KT Han, JI Sin - Cancer letters, 2015 - Elsevier
Human colon cancers express carcinoembryonic antigen (CEA). Thus, CEA has been
considered as a potential vaccine target for immune therapy against colon cancer. In this …
considered as a potential vaccine target for immune therapy against colon cancer. In this …
Signal sequence deletion and fusion to tetanus toxoid epitope augment antitumor immune responses to a human carcinoembryonic antigen (CEA) plasmid DNA …
LH Lund, K Andersson, B Zuber, A Karlsson… - Cancer gene …, 2003 - nature.com
Abstract Carcinoembryonic antigen (CEA, CEACAM5) is expressed on several human
carcinomas including colon cancer. CEA contains signal peptides that target the protein …
carcinomas including colon cancer. CEA contains signal peptides that target the protein …
Carcinoembryonic antigen (CEA) presentation and specific T cell-priming by human dendritic cells transfected with CEA-mRNA
E Eppler, H Hörig, HL Kaufman, P Groscurth… - European Journal of …, 2002 - Elsevier
The feasibility of dendritic cells (DC) for cancer immunotherapy after transfection by
electroporation with mRNA encoding the human carcinoembryonic antigen (CEA) was …
electroporation with mRNA encoding the human carcinoembryonic antigen (CEA) was …
Dendritic cells transduced with recombinant adenoviruses induce more efficient anti-tumor immunity than dendritic cells pulsed with peptide
ST Oh, CH Kim, MY Park, EH Won, HJ Sohn, HI Cho… - Vaccine, 2006 - Elsevier
Transduction with recombinant, replication-defective adenovirus (AdV) vectors encoding a
transgene is an efficient method for gene transfer into murine or human dendritic cells (DC) …
transgene is an efficient method for gene transfer into murine or human dendritic cells (DC) …
Induction of mucosal and systemic immune responses against human carcinoembryonic antigen by an oral vaccine
Y Huang, R Fayad, A Smock, AM Ullrich, L Qiao - Cancer research, 2005 - AACR
Carcinoembryonic antigen (CEA) is a tumor-associated antigen targeted for the
development of colorectal tumor vaccines. In this study, we developed papillomavirus …
development of colorectal tumor vaccines. In this study, we developed papillomavirus …
Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity
JW Greiner, H Zeytin, MR Anver, J Schlom - Cancer research, 2002 - AACR
By virtue of its tissue-specific expression, carcinoembryonic antigen (CEA) is an important
self, tumor-associated antigen, which is expressed by different human adenocarcinomas …
self, tumor-associated antigen, which is expressed by different human adenocarcinomas …