Generation and characterization of monoclonal antibodies against the hemagglutinin of H3N2 influenza A viruses
F Yang, L Zhu, F Liu, L Cheng, H Yao, N Wu, H Wu, L Li - Virus Research, 2022 - Elsevier
Seasonal influenza viruses are highly contagious, leading to 290,000–650,000 mortalities
every year globally. Among the influenza viruses, influenza A virus (H3N2) has attracted …
every year globally. Among the influenza viruses, influenza A virus (H3N2) has attracted …
Characterization of neutralizing epitopes in antigenic site B of recently circulating influenza A (H3N2) viruses
K Beer, M Dai, S Howell, P Rijal… - Journal of General …, 2018 - microbiologyresearch.org
Influenza A (H3N2) viruses are associated with outbreaks worldwide and can cause disease
with severe complications. The impact can be reduced by vaccination, which induces …
with severe complications. The impact can be reduced by vaccination, which induces …
A human antibody recognizing a conserved epitope of H5 hemagglutinin broadly neutralizes highly pathogenic avian influenza H5N1 viruses
Influenza A virus infection is a persistent threat to public health worldwide due to its ability to
evade immune surveillance through rapid genetic drift and shift. Current vaccines against …
evade immune surveillance through rapid genetic drift and shift. Current vaccines against …
Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin
Due to continuous changes to its antigenic regions, influenza viruses can evade immune
detection and cause a significant amount of morbidity and mortality around the world …
detection and cause a significant amount of morbidity and mortality around the world …
Development and characterization of a panel of cross-reactive monoclonal antibodies generated using H1N1 influenza virus
C Guo, Y Tang, Z Qi, Y Liu, X Zhao, X Huo, Y Li, Q Feng… - Immunobiology, 2015 - Elsevier
To characterize the antigenic epitopes of the hemagglutinin (HA) protein of H1N1 influenza
virus, a panel consisting of 84 clones of murine monoclonal antibodies (mAbs) were …
virus, a panel consisting of 84 clones of murine monoclonal antibodies (mAbs) were …
Generation, characterization, and protective ability of mouse monoclonal antibodies against the HA of A (H1N1) influenza virus
L Wang, F Yang, Y Xiao, B Chen, F Liu… - Journal of medical …, 2022 - Wiley Online Library
Influenza virus infections pose a continuous threat to human health. Although vaccines
function as a preventive and protective tool, they may not be effective due to antigen drift or …
function as a preventive and protective tool, they may not be effective due to antigen drift or …
A human monoclonal antibody derived from a vaccinated volunteer recognizes heterosubtypically a novel epitope on the hemagglutinin globular head of H1 and H9 …
N Boonsathorn, S Panthong, S Koksunan… - Biochemical and …, 2014 - Elsevier
Most neutralizing antibodies elicited during influenza virus infection or by vaccination have a
narrow spectrum because they usually target variable epitopes in the globular head region …
narrow spectrum because they usually target variable epitopes in the globular head region …
Monoclonal antibody targeting neutralizing epitope on H5N1 influenza virus of clade 1 and 0 for specific H5 quantification
F He, J Kwang - Influenza Research and Treatment, 2013 - Wiley Online Library
H5N1 influenza viruses cause high mortality in avian and mammalian species, including
humans. Antigenic drift in H5 sequence poses challenges in the development of vaccine …
humans. Antigenic drift in H5 sequence poses challenges in the development of vaccine …
Antibodies to antigenic site A of influenza H7 hemagglutinin provide protection against H7N9 challenge
F Schmeisser, A Vasudevan, S Verma, W Wang… - PloS one, 2015 - journals.plos.org
Identifying major antigenic and protective epitopes of the H7 hemagglutinin (HA) will be
important for understanding the antibody response to vaccines developed against the novel …
important for understanding the antibody response to vaccines developed against the novel …
Hemagglutinin stalk-based monoclonal antibody elicits broadly reactivity against group 1 influenza A virus
J Huang, N Huang, M Fan, L Zhao, Y Luo, P Ding… - Virology Journal, 2020 - Springer
Background Influenza virus remains a continuous and severe threat to public health
worldwide, and its prevention and treatment have always been a major international issue …
worldwide, and its prevention and treatment have always been a major international issue …