48 EFFECTS OF TRICHOSTATIN A ON DEVELOPMENT OF BOVINE SOMATIC CELL NUCLEAR TRANSFER EMBRYOS

D Iwamoto, K Saeki, S Kishigami… - Reproduction …, 2007 - CSIRO Publishing
Although cloning by somatic cell nuclear transfer (SCNT) has been achieved in various
mammalian species, its efficiency has been very low (Han et al. 2003 Theriogenology 59, 33 …

43 SHORT-AND LONG-LASTING EFFECTS OF TRICHOSTATIN A TREATMENT OF SCNT EMBRYOS IN CATTLE

I Lagutina, R Duchi, S Colleoni… - Reproduction, Fertility …, 2010 - CSIRO Publishing
Both preimplantation and full-term development of mouse somatic cell nuclear transfer
(SCNT) embryos are significantly enhanced by treatment with trichostatin A (TSA), an …

45 EFFECT OF TRICHOSTATIN A TREATMENT ON THE TERM DEVELOPMENT OF SOMATIC CELL NUCLEAR TRANSFER RABBIT EMBRYOS

Q Meng, Z Polgar, J Liu, A Dinnyes - Reproduction, Fertility and …, 2007 - CSIRO Publishing
The efficiency of somatic cell nuclear transfer (SCNT) is low in the rabbit. So far, there have
been few live births reported and most clones died within the first 3 weeks after birth. It has …

24 EFFECT OF TREATMENT WITH TRICHOSTATIN A ON IN VITRO DEVELOPMENT OF BOVINE NUCLEAR-TRANSFERRED EMBRYOS

S Akagi, K Fukunari, K Matsukawa… - Reproduction …, 2006 - CSIRO Publishing
It has been reported that 5 or 50 nM trichostatin A (TSA) treatment after somatic cell nuclear
transfer (NT) improves the success rate of mouse cloning (Kishigami et al. 2006 Biochem …

Trichostatin A promotes the development of bovine somatic cell nuclear transfer embryos

MJ Lee, SW Kim, HG Lee, GS Im, BC Yang… - … of Reproduction and …, 2011 - jstage.jst.go.jp
We studied the effects of trichostatin A (TSA), a histone deacetylase inhibitor, on the
development of bovine somatic cell nuclear transfer (SCNT) embryos by investigating (1) the …

Effects of trichostatin A on histone acetylation and methylation characteristics in early porcine embryos after somatic cell nuclear transfer

P Cong, K Zhu, Q Ji, H Zhao, Y Chen - Animal Science Journal, 2013 - Wiley Online Library
Until now, the efficiency of animal cloning by somatic cell nuclear transfer (SCNT) has
remained low. Efforts to improve cloning efficiency have demonstrated a positive role of …

Extended exposure to trichostatin A after activation alters the expression of genes important for early development in nuclear transfer murine embryos

H Kang, S Roh - Journal of Veterinary Medical Science, 2011 - jstage.jst.go.jp
The low viability of embryos reconstructed by somatic cell nuclear transfer (SCNT) is
believed to be associated with epigenetic modification errors, and reduction of those errors …

[HTML][HTML] Effects of trichostatin A on in vitro development of porcine embryos derived from somatic cell nuclear transfer

YI Jeong, CH Park, HS Kim, YW Jeong… - … journal of animal …, 2013 - ncbi.nlm.nih.gov
Many different approaches have been developed to improve the efficiency of animal cloning
by somatic cell nuclear transfer (SCNT), one of which is to modify histone acetylation levels …

Comparison of Blastocyst Development between Cat-Cow and Cat-Pig Interspecies Somatic Cell Nuclear Transfer Embryos Treated with Trichostatin A

LTK Do, M Wittayarat, Y Sato, K Chatdarong… - Biology Bulletin, 2021 - Springer
We previously demonstrated that the histone deacetylase inhibitor, trichostatin A (TSA),
improves the development of cat-cow interspecies somatic cell nuclear transfer (iSCNT) …

Effects of Trichostatin A on the Timing of the First Cleavage and In Vitro Developmental Potential of Bovine Somatic Cell Nuclear Transfer Embryos

S Akagi, K Matsukawa - Cellular Reprogramming, 2022 - liebertpub.com
This study examined the relationship between the timing of the first cleavage and in vitro
development of bovine somatic cell nuclear transfer (SCNT) embryos treated with …