28 EFFECT OF TRICHOSTATIN A ON IN VITRO EMBRYO DEVELOPMENT OF INTERSPECIES NUCLEAR TRANSFER EMBRYOS RECONSTRUCTED FROM CAT …
M Wittayarat, Z Namula, VV Luu, LTK Do… - Reproduction, fertility …, 2012 - CSIRO Publishing
Interspecies somatic cell nuclear transfer (iSCNT) is an invaluable tool for studying nucleus-
cytoplasm interactions and may provide an alternative for cloning endangered animals …
cytoplasm interactions and may provide an alternative for cloning endangered animals …
Trichostatin A affects histone acetylation and gene expression in porcine somatic cell nucleus transfer embryos
RP Cervera, N Marti-Gutierrez, E Escorihuela… - Theriogenology, 2009 - Elsevier
Epigenetic aberrancies likely preclude correct and complete nuclear reprogramming after
somatic cell nucleus transfer (SCNT) and may underlie the observed reduced viability of …
somatic cell nucleus transfer (SCNT) and may underlie the observed reduced viability of …
Donor cell trichostatin A treatment improves the in vitro development of cloned goat embryos
YM Wang, XB Ding, XF Liu, Y Zhang - Small Ruminant Research, 2015 - Elsevier
The low success rate of somatic cell nuclear transfer (SCNT) is primarily due to incomplete
reprogramming of the transferred nuclei. As an inhibitor of histone deacetylase, trichostatin A …
reprogramming of the transferred nuclei. As an inhibitor of histone deacetylase, trichostatin A …
An Epigenetic Modifier Results in Improved In Vitro Blastocyst Production after Somatic Cell Nuclear Transfer
Y Zhang, J Li, K Villemoes, AM Pedersen… - Cloning and stem …, 2007 - liebertpub.com
The present study was designed to examine the effect of trichostatin A (TSA), an inhibitor of
histone deacetylase, on development of porcine cloned embryos. Our results showed that …
histone deacetylase, on development of porcine cloned embryos. Our results showed that …
Trichostatin A improves histone acetylation in bovine somatic cell nuclear transfer early embryos
Epigenetic aberrancies likely preclude correct and complete nuclear reprogramming
following somatic cell nuclear transfer (SCNT), and may underlie the observed reduced …
following somatic cell nuclear transfer (SCNT), and may underlie the observed reduced …
Comparison of potency between histone deacetylase inhibitors trichostatin A and valproic acid on enhancing in vitro development of porcine somatic cell nuclear …
YJ Kim, KS Ahn, M Kim, H Shim - In Vitro Cellular & Developmental Biology …, 2011 - Springer
Epigenetic modification influences reprogramming and subsequent development of somatic
cell nuclear transfer (SCNT) embryos. Such modification includes an increase in histone …
cell nuclear transfer (SCNT) embryos. Such modification includes an increase in histone …
Treatment with a histone deacetylase inhibitor after nuclear transfer improves the preimplantation development of cloned bovine embryos
S Akagi, K Matsukawa, E Mizutani… - … of Reproduction and …, 2011 - jstage.jst.go.jp
We examined the effects of treatment with histone deacetylase inhibitors (HDACi),
trichostatin A (TSA) and scriptaid (SCR), on the blastocyst formation rate in bovine somatic …
trichostatin A (TSA) and scriptaid (SCR), on the blastocyst formation rate in bovine somatic …
Effects of Trichostatin A and 5-aza-2'deoxycytidine on Nuclear Reprogramming in Pig Cloned Embryos
SH Lee, YN Xu, YT Heo, XS Cui… - Reproductive and …, 2013 - koreascience.kr
Low efficiency of somatic cell nuclear transfer (SCNT) is attributed to incomplete
reprogramming of transfered nuclei into oocytes. Trichostatin A (TSA), histone deacetylase …
reprogramming of transfered nuclei into oocytes. Trichostatin A (TSA), histone deacetylase …
139 TRICHOSTATIN A IMPROVED IN VITRO DEVELOPMENT OF PORCINE NUCLEAR TRANSFER EMBRYOS PRODUCED BY A NEW ACTIVATION METHOD
LC Sui, W Wang, YS Li, YL Zhang, SF Ji… - Reproduction …, 2010 - CSIRO Publishing
Recently, it has been reported that a new activation method, brief exposure to cycloheximide
before electrical activation, could increase development rates and reduce cell death. In our …
before electrical activation, could increase development rates and reduce cell death. In our …
Histone deacetylase inhibitor improves the development and acetylation levels of cat–cow interspecies cloned embryos
M Wittayarat, Y Sato, LTK Do, Y Morita… - … " Cloning and Stem …, 2013 - liebertpub.com
Abnormal epigenetic reprogramming, such as histone acetylation, might cause low
efficiency of interspecies somatic cell nuclear transfer (iSCNT). This study was conducted to …
efficiency of interspecies somatic cell nuclear transfer (iSCNT). This study was conducted to …