This study was carried out to investigate the effect of trichostatin A (TSA) treatment on
interspecies cloned gaur (Bos gaurus) embryos development and implantation rate after …

Although somatic cell nuclear transfer (SCNT) can be used to create transgenic pigs for
human xenotransplantation, low efficiency limits its use. Trichostatin A (TSA) promotes …

Trichostatin A (TSA), a histone deacetylase (HDAC) inhibitor, can significantly improve the
reprogramming efficiency of somatic cells. However, whether TSA has a detrimental effect …

Derivation of embryonic stem cells from patient-specific cloned blastocysts by somatic cell
nuclear transfer (SCNT) holds promise for both regenerative medicine and cell-based drug …

We report here the establishment and characterization of putative porcine embryonic stem
cell (ESC) lines derived from somatic cell nuclear transfer embryos (NT-ESCs). These cells …

Although the somatic cloning technique has been used for numerous applications and basic
research of reprogramming in various species, extremely low success rates have plagued …

Here, the study aimed to improve the developmental competence of porcine SCNT embryos
using Trichostatin A (TSA) and Scriptaid which are well known as histone deacetylase …

Somatic cell nuclear transfer (SCNT) is a useful technique for the production of transgenic
pigs that can be used for biomedical research. However, the efficiency of SCNT in pigs is …

The present study evaluated the effect of Scriptaid, a novel histone deacetylase inhibitor
(HDACi), on the in vitro development of somatic cell nuclear transfer (SCNT) bovine …

Low cloning efficiency is considered to be caused by the incomplete or aberrant epigenetic
reprogramming of differentiated donor cells in somatic cell nuclear transfer (SCNT) embryos …