In this review, we summarize the mechanisms by which sphingolipids modulate virus
multiplication and the host innate immune response, using a number of host-virus systems …

Sphingosine 1-phosphate (S1P)-metabolizing enzymes regulate the level of bioactive
sphingolipids that have curative potential. Recently, S1P-metabolizing enzymes such as …

Besides their essential role in the immune system, sphingolipids and their metabolites are
potential key regulators in the life cycle of obligatory intracellular pathogens such as viruses …

Sphingolipids are involved in cell signaling and metabolic pathways, and their metabolites
play a critical role in host defense against intracellular pathogens. Here, we review the …

Viruses attempt to create a distinctive cellular environment to favor viral replication and
spread. Recent studies uncovered new functions of the sphingolipid signaling/metabolism …

Sphingolipids are essential components of eukaryotic cells. In this review, we want to
exemplarily illustrate what is known about the interactions of sphingolipids with various …

Cellular sphingolipids have vital roles in human virus replication and spread as they are
exploited by viruses for cell entry, membrane fusion, genome replication, assembly …

As viruses are obligatory intracellular parasites, any step during their life cycle strictly
depends on successful interaction with their particular host cells. In particular, their …

HIV-1 infects host cells by sequential interactions of its fusion protein (gp120-gp41) with
receptors CD4, CXCR4 and/or CCR5 followed by fusion of viral and host membranes …

Viruses exploit membranes and their components such as sphingolipids in all steps of their
life cycle including attachment and membrane fusion, intracellular transport, replication …