Crossroads of coagulation and innate immunity: the case of deep vein thrombosis

C Schulz, B Engelmann… - Journal of thrombosis and …, 2013 - Wiley Online Library
Deep vein thrombosis (DVT) is a common condition characterized by the formation of an
occlusive blood clot in the venous vascular system, potentially complicated by detachment …

[HTML][HTML] Immune factors in deep vein thrombosis initiation

I Budnik, A Brill - Trends in immunology, 2018 - cell.com
Deep vein thrombosis (DVT) is a major origin of morbidity and mortality. While DVT has long
been considered as blood coagulation disorder, several recent lines of evidence …

Resolution of deep venous thrombosis: proposed immune paradigms

JM Nicklas, AE Gordon, PK Henke - International Journal of Molecular …, 2020 - mdpi.com
Venous thromboembolism (VTE) is a pathology encompassing deep vein thrombosis (DVT)
and pulmonary embolism (PE) associated with high morbidity and mortality. Because …

Pathophysiology of deep vein thrombosis

S Navarrete, C Solar, R Tapia, J Pereira… - Clinical and …, 2023 - Springer
Deep venous thrombosis is a frequent, multifactorial disease and a leading cause of
morbidity and mortality. Most of the time deep venous thrombosis is triggered by the …

The role of neovascularisation in the resolution of venous thrombus

B Modarai, KG Burnand, J Humphries… - Thrombosis and …, 2005 - thieme-connect.com
Deep vein thrombosis (DVT) can give rise to chronic debilitating complications, which are
expensive to treat. Anticoagulation, the standard therapy for DVT, prevents propagation, but …

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

ML von Brühl, K Stark, A Steinhart… - Journal of Experimental …, 2012 - rupress.org
Deep vein thrombosis (DVT) is a major cause of cardiovascular death. The sequence of
events that promote DVT remains obscure, largely as a result of the lack of an appropriate …

Leukocytes and the natural history of deep vein thrombosis: current concepts and future directions

P Saha, J Humphries, B Modarai… - … , and vascular biology, 2011 - Am Heart Assoc
Observational studies have shown that inflammatory cells accumulate within the thrombus
and surrounding vein wall during the natural history of venous thrombosis. More recent …

Fibrinolysis and inflammation in venous thrombus resolution

S Mukhopadhyay, TA Johnson, N Duru… - Frontiers in …, 2019 - frontiersin.org
Clinical observations and accumulating laboratory evidence support a complex interplay
between coagulation, inflammation, innate immunity and fibrinolysis in venous …

Multiple facets of venous thrombosis

A Brill - International Journal of Molecular Sciences, 2021 - mdpi.com
Venous thromboembolism, a complex disease combining deep vein thrombosis (DVT) and
its most dangerous complication, pulmonary embolism (PE), strikes millions of people …

Inflammation in deep vein thrombosis: a therapeutic target?

D Borgel, E Bianchini, D Lasne, T Pascreau, F Saller - Hematology, 2019 - Taylor & Francis
Deep vein thrombosis is a common disease associated with a variety of complications
including post-thrombotic syndrome as a late complication. It is now clear that in addition to …