Capsaicin applied locally to a coccygeal or saphenous nerve of rats was shown to block
impulse conduction in unmyelinated afferent nerve fibres. Shortly after application of …

We investigated the action of capsazepine, an antagonist of the actions of capsaicin on
sensory neurones, on the contractile responses evoked by capsaicin or by electrical field …

A series of analogues of capsaicin, the pungentprinciple of chilli peppers, was synthesized
and tested in assays for capsaicin-like agonism in vitro. The results of these assays were …

An action of capsaicin was investigated on dorsal root-evoked synaptic transmission to
substantia gelatinosa (SG) neurons in adult rat spinal cord slices by use of the whole-cell …

Using a positron emission tomography (PET) study it was shown recently that in migraine
without aura certain areas in the brain stem were activated during the headache state, but …

Two-day-old rats were pretreated with 50 mg/kg of capsaicin. After 3–4 months, specific
binding of [3 H] muscimol and [3 H] strychnine was measured in membrane preparations …

Studying the visceral effects of the sensory stimulant capsaicin is a useful and relatively
simple tool of neurotransmitter identification and has been used for this purpose for …

Systemic capsaicin treatment of neonatal and adult rats is known to affect unmyelinated
afferents. However, the systemic route of administration presents several disadvantages and …

Results Intravenous administration of capsaicin. Capsaicin levels in tissues 3 and 10 min
after iv injection of 2 mg kg-1 are shown in Table 1. Three minutes after iv administration an …