Background Pregnancy associated malaria is a severe clinical syndrome associated with
sequestration of Plasmodium falciparum-infected erythrocytes in the placenta. Placental …

During placental malaria, Plasmodium falciparum infected erythrocytes sequester in the
placenta, causing health problems for both the mother and fetus. The specific adherence is …

Protection against maternal malaria has been associated with the acquisition of a specific
antibody response that prevents adhesion of Plasmodium falciparum‐infected erythrocytes …

Gender-specific and parity-dependent acquired antibody recognition is characteristic of
variant surface antigens (VSA) expressed by chondroitin sulfate A (CSA)-adherent …

Background In Plasmodium falciparum malaria endemic areas placental malaria (PM) is an
important complication of malaria. The recurrence of malaria in primigravidae women …

Molecular interactions between the VAR2CSA protein, expressed on the surface of
Plasmodium falciparum-infected erythrocytes, and placental chondroitin sulfate A (CSA) are …

In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA
antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding …

Over 50 million women are exposed to the risk of malaria during pregnancy every year.
Malaria during pregnancy is a leading global cause of maternal morbidity and adverse …

Placental malaria is a serious problem in sub-Saharan Africa. Young women are particular
susceptible to contracting this form of malaria during their first or second pregnancy despite …

Plasmodium falciparum placental parasites from Cameroon have been shown to express
surface variant var genes encoding Duffy binding–like (DBL)–γ domains that bind …