Background VAR2CSA, a member of the Plasmodium falciparum erythrocyte membrane
protein 1 (PfEMP1) family, mediates the binding of P. falciparum-infected erythrocytes to …

Placental malaria (PM) due to Plasmodium falciparum is a major cause of maternal, fetal
and infant mortality, but the mechanisms of pathogenesis and protective immunity are …

Chondroitin sulfate A (CSA) is an important receptor for the sequestration of Plasmodium
falciparum in the placenta, but the parasite ligand involved in adhesion has not previously …

Background. Pregnancy-associated malaria is characterized by selection and multiplication,
in the placenta, of a distinct population of Plasmodium falciparum expressing particular …

Malaria during pregnancy is a major health problem for African women. The disease is
caused by Plasmodium falciparum malaria parasites, which accumulate in the placenta by …

Background. Plasmodium falciparum–infected erythrocytes (IEs) adhere to host cell
receptors, allowing parasites to sequester into deep vascular beds of various organs. This …

Background. Plasmodium falciparum-infected erythrocytes adhere to chondroitin sulfate A
(CSA) to sequester in the human placenta, and pregnancy malaria (PM) is associated with …

Malaria during pregnancy is a major global health problem caused by infection with
Plasmodium falciparum parasites. Severe effects arise from the accumulation of infected …

Abstract Background In pregnancy, Plasmodium falciparum parasites express the surface
antigen VAR2CSA, which mediates adherence of red blood cells to chondroitin sulfate A …

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family mediates
parasite sequestration in small capillaries through tissue-specific cytoadherence. The best …