[HTML][HTML] Protective antibodies against placental malaria and poor outcomes during pregnancy, Benin
NT Ndam, L Denoeud-Ndam… - Emerging infectious …, 2015 - ncbi.nlm.nih.gov
Placental malaria is caused by Plasmodium falciparum–infected erythrocytes that bind to
placental tissue. Binding is mediated by VAR2CSA, a parasite antigen coded by the var …
placental tissue. Binding is mediated by VAR2CSA, a parasite antigen coded by the var …
A single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates
JYA Doritchamou, JP Renn, B Jenkins, A Mahamar… - Elife, 2022 - elifesciences.org
Placental malaria (PM) is a deadly syndrome most frequent and severe in first pregnancies.
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …
Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity
JP Renn, JYA Doritchamou, BCN Tentokam… - Communications …, 2021 - nature.com
Plasmodium falciparum-infected erythrocytes (IE) sequester in the placenta via surface
protein VAR2CSA, which binds chondroitin sulfate A (CSA) expressed on the …
protein VAR2CSA, which binds chondroitin sulfate A (CSA) expressed on the …
Functional antibodies against VAR2CSA in nonpregnant populations from colombia exposed to Plasmodium falciparum and Plasmodium vivax
S Gnidehou, J Doritchamou, EM Arango… - Infection and …, 2014 - Am Soc Microbiol
In pregnancy, parity-dependent immunity is observed in response to placental infection with
Plasmodium falciparum. Antibodies recognize the surface antigen, VAR2CSA, expressed on …
Plasmodium falciparum. Antibodies recognize the surface antigen, VAR2CSA, expressed on …
[HTML][HTML] Characterization of anti-var2CSA-PfEMP1 cytoadhesion inhibitory mouse monoclonal antibodies
Pregnancy-associated malaria (PAM) is associated with the massive sequestration of
erythrocytes infected with CSA-binding parasites in the placenta. Natural protective immunity …
erythrocytes infected with CSA-binding parasites in the placenta. Natural protective immunity …
Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive antibodies
B Bordbar, N Tuikue-Ndam, P Bigey, J Doritchamou… - Vaccine, 2012 - Elsevier
PURPOSE OF THE RESEARCH: VAR2CSA is considered as the main target of protective
immunity against pregnancy-associated malaria. VAR2CSA high molecular weight …
immunity against pregnancy-associated malaria. VAR2CSA high molecular weight …
Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A
K Singh, AG Gittis, P Nguyen, DC Gowda… - Nature structural & …, 2008 - nature.com
Plasmodium falciparum–infected erythrocytes bind to chondroitin sulfate A (CSA) in the
placenta via the VAR2CSA protein, a member of the P. falciparum erythrocyte membrane …
placenta via the VAR2CSA protein, a member of the P. falciparum erythrocyte membrane …
The effect of adjuvants on the immune response induced by a DBL4ɛ-ID4 VAR2CSA based Plasmodium falciparum vaccine against placental malaria
VV Pinto, A Salanti, LM Joergensen, M Dahlbäck… - Vaccine, 2012 - Elsevier
A vaccine protecting women against placental malaria could be based on the sub-domains
of the VAR2CSA antigen, since antibodies against the DBL4ɛ-ID4 subunit of the VAR2CSA …
of the VAR2CSA antigen, since antibodies against the DBL4ɛ-ID4 subunit of the VAR2CSA …
Molecular dissection of placental malaria protein VAR2CSA interaction with a chemo-enzymatically synthesized chondroitin sulfate library
N Sugiura, TM Clausen, T Shioiri, T Gustavsson… - Glycoconjugate …, 2016 - Springer
Placental malaria, a serious infection caused by the parasite Plasmodium falciparum, is
characterized by the selective accumulation of infected erythrocytes (IEs) in the placentas of …
characterized by the selective accumulation of infected erythrocytes (IEs) in the placentas of …
Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA
M Avril, BR Kulasekara, SO Gose, C Rowe… - Infection and …, 2008 - Am Soc Microbiol
Pregnancy-associated malaria (PAM) is characterized by the placental sequestration of
Plasmodium falciparum-infected erythrocytes (IEs) with the ability to bind to chondroitin …
Plasmodium falciparum-infected erythrocytes (IEs) with the ability to bind to chondroitin …