The Plasmodium falciparum multigene var family codes for approximately 50 variant
adhesive proteins expressed in a mutually exclusive manner at the surface of infected red …

Pregnancy‐associated Plasmodium falciparum malaria (PAM) is a major cause of morbidity
and mortality in African women and their offspring. PAM is characterized by accumulation of …

Sequestration of Plasmodium falciparum‐infected erythrocytes in the placenta is responsible
for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result …

The VAR2CSA protein of Plasmodium falciparum is transported to and expressed on the
infected erythrocyte surface where it plays a key role in placental malaria (PM). It is the …

Malaria is undoubtedly the world's most devastating parasitic disease, affecting 300 to 500
million people every year. Some cases of Plasmodium falciparum infection progress to the …

The variant surface antigen VAR2CSA is a pregnancy malaria vaccine candidate, but its size
and polymorphism are obstacles to development. We expressed 3D7-type VAR2CSA …

VAR2CSA mediates sequestration of Plasmodium falciparum-infected erythrocytes in the
placenta, increasing the risk of poor pregnancy outcomes. Naturally acquired antibodies …

The malaria parasite Plasmodium falciparum presents antigens on the infected erythrocyte
surface that bind human receptors expressed on the vascular endothelium. The VAR2CSA …

Plasmodium falciparum infected erythrocytes (IE) accumulate in the placenta through the
interaction between Duffy-binding like (DBL) domains of parasite-encoded ligand VAR2CSA …

Pregnancy-associated malaria is a major health problem, which mainly affects primigravidae
living in malaria endemic areas. The syndrome is precipitated by accumulation of infected …