A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium
Cryptosporidium spp are well recognised as causes of diarrhoeal disease during
waterborne epidemics and in immunocompromised hosts. Studies have also drawn …
waterborne epidemics and in immunocompromised hosts. Studies have also drawn …
Towards a vaccine for Cryptococcus neoformans: principles and caveats
K Datta, L Pirofski - FEMS yeast research, 2006 - academic.oup.com
In the Damage-response framework of microbial pathogenesis, infectious diseases are one
outcome of a host-microorganism interaction in a susceptible host. In cryptococcal disease …
outcome of a host-microorganism interaction in a susceptible host. In cryptococcal disease …
An update on Cryptococcus among HIV-infected patients
T Warkentien… - International journal of …, 2010 - journals.sagepub.com
Cryptococcus remains an important opportunistic infection in HIV patients despite
considerable declines in prevalence during the highly active antiretroviral therapy era. This …
considerable declines in prevalence during the highly active antiretroviral therapy era. This …
[HTML][HTML] Challenges and prospects for a Cryptosporidium vaccine
JR Mead - Future Microbiology, 2010 - Future Medicine
Editorial Mead do not know how much cross-protection develops between
genotypes/species, the role the initial dose plays in establishing long-term memory cell …
genotypes/species, the role the initial dose plays in establishing long-term memory cell …
[HTML][HTML] Insights into the Mechanisms of Protective Immunity against Cryptococcus neoformans Infection Using a Mouse Model of Pulmonary Cryptococcosis
KL Wozniak, S Ravi, S Macias, ML Young… - PloS one, 2009 - journals.plos.org
Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
pneumonia and meningoencephalitis in immune compromised individuals. Previous studies …
pneumonia and meningoencephalitis in immune compromised individuals. Previous studies …
Cryptococcal meningitis
Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …
Are macrophages the heroes or villains during cryptococcosis?
J Rudman, RJ Evans, SA Johnston - Fungal Genetics and Biology, 2019 - Elsevier
Cryptococcus infections represents a major healthcare burden, with over 200,000 cases
globally a year and even with treatment, mortality remains as high as 80%. There is a clear …
globally a year and even with treatment, mortality remains as high as 80%. There is a clear …
[HTML][HTML] Cryptococcal virulence in humans: Learning from translational studies with clinical isolates
HR De Sousa, S Frazão, GP Oliveira Júnior… - Frontiers in Cellular …, 2021 - frontiersin.org
Cryptococcosis, an invasive mycosis caused by Cryptococcus spp, kills between 20% and
70% of the patients who develop it. There are no vaccines for prevention, and treatment is …
70% of the patients who develop it. There are no vaccines for prevention, and treatment is …
Cryptococcus: from environmental saprophyte to global pathogen
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …
Preventing deaths from cryptococcal meningitis: from bench to bedside
M Roy, T Chiller - Expert review of anti-infective therapy, 2011 - Taylor & Francis
Cryptococcal meningitis (CM), a fungal disease caused by Cryptococcus spp., is the most
common form of meningitis and a leading cause of death among persons with HIV/AIDS in …
common form of meningitis and a leading cause of death among persons with HIV/AIDS in …