Focal segmental glomerulosclerosis (FSGS) is characterized by steroid resistant nephrotic
syndrome and progression to end-stage renal disease. Proteinuria in certain patients with …

The presence of circulating plasma factors (PF) altering renal permeability to proteins has
been previously described in patients with focal segmental glomerulosclerosis (FSGS) …

The pathogenesis of primary focal segmental glomerulosclerosis (FSGS) and minimal
change disease (MCD) remains unknown to date. Some circulating permeability factors are …

Idiopathic NS (nephrotic syndrome) is characterized by massive proteinuria, due to a leak in
the glomerular barrier to proteins. Genetic defects that affect the function and the …

Therapy-resistant nephrotic syndrome in children is generally based on primary focal
segmental glomerulosclerosis (pFSGS) and will lead to deterioration of kidney function …

Background Nephrotic syndrome (NS) in children has been associated with a systemic
circulating permeability factor. Therefore, once peritoneal dialysis (PD) has been started …

United States, particularly for African Americans, for whom the lifetime risk of developing
FSGS may approach 1%. 1 FSGS traditionally has been classified into 3 categories:(1) rare …

Primary focal segmental glomerulosclerosis (FSGS) is a major cause of the nephrotic
syndrome and often leads to end‐stage renal disease. This review focuses on circulating …

Background: A circulating factor that increases in vitro glomerular permeability to albumin
(Palb) has been isolated from patients with recurrence of focal segmental …

The putative mechanisms of proteinuria in idiopathic focal glomerulosclerosis and of its post‐
transplant recurrence are discussed. It is proposed that a balance between circulating …