Cytapheresis in inflammatory bowel diseases: current evidence and perspectives

S Danese, E Angelucci, T Stefanelli, P Omodei… - Digestion, 2008 - karger.com
Ulcerative colitis and Crohn's disease are inflammatory bowel diseases with a chronic
relapsing course. Management of both conditions is far from being fully satisfactory. For this …

Leukocytapheresis in the treatment of inflammatory bowel disease: Current position and perspectives

P Vernia, V D'Ovidio, D Meo - Transfusion and Apheresis Science, 2010 - Elsevier
Therapeutic apheresis, a novel approach for immunodisorders, has been used in the last
decade for the treatment of ulcerative colitis with promising result, and represents an …

Selective leukocyte apheresis for the treatment of inflammatory bowel disease

MT Abreu, S Plevy, BE Sands… - Journal of clinical …, 2007 - journals.lww.com
The etiology of inflammatory bowel disease (IBD) is not completely understood, thus current
therapies have been empirical and directed at treating symptoms rather than addressing the …

The logics of leukocytapheresis as a natural biological therapy for inflammatory bowel disease

T Kanai, T Hibi, M Watanabe - Expert Opinion on Biological …, 2006 - Taylor & Francis
Ulcerative colitis (UC) and Crohn's disease (CD) are debilitating idiopathic inflammatory
bowel diseases (IBDs) with symptoms that impair ability to function and quality of life. The …

Recent understanding of leukocytapheresis (LCAP) for the treatment of inflammatory bowel disease

K Mitsuyama, H Yamasaki, K Kuwaki… - Current …, 2009 - ingentaconnect.com
Inflammatory bowel disease (IBD) is frequently associated with the infiltration of a large
number of leukocytes into the bowel mucosa. Therefore, the removal of circulating …

[HTML][HTML] Positions of selective leukocytapheresis in the medical therapy of ulcerative colitis

H Hanai - World Journal of Gastroenterology: WJG, 2006 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) and Crohn's disease (CD) are the major forms of idiopathic
inflammatory bowel disease (IBD). Both UC and CD are debilitating chronic disorders that …

Adacolumn leucocytapheresis for ulcerative colitis: clinical and endoscopic features of responders and unresponders

R Sacco, T Tanaka, T Yamamoto, G Bresci… - Expert Review of …, 2015 - Taylor & Francis
Cytokines such as TNF-α have a validated role in the immunopathogensis of ulcerative
colitis (UC), and intercepting inflammatory cytokines is currently the best option for …

Pilot feasibility studies of leukocytapheresis with the Adacolumn Apheresis System in patients with active ulcerative colitis or Crohn disease

BE Sands, WJ Sandborn, DC Wolf, S Katz… - Journal of clinical …, 2006 - journals.lww.com
Background Patients with UC and CD, characterized by elevations in peripheral blood
granulocytes, monocytes/macrophages, and proinflammatory mediators, may benefit from …

Granulomonocytapheresis as a cell‐dependent treatment option for patients with inflammatory bowel disease: concepts and clinical features for better therapeutic …

AR Saniabadi, T Tanaka, T Yamamoto… - Journal of clinical …, 2019 - Wiley Online Library
Ulcerative colitis (UC) and Crohn's disease (CD) are major phenotypes of the chronic
inflammatory bowel disease (IBD), which afflicts millions of individuals throughout the world …

Adacolumn for selective leukocytapheresis as a non‐pharmacological treatment for patients with disorders of the immune system: an adjunct or an alternative to drug …

AR Saniabadi, H Hanai, Y Suzuki… - Journal of Clinical …, 2005 - Wiley Online Library
Inflammatory and/or autoimmune diseases like ulcerative colitis (UC) or Crohn's disease
(CD) are debilitating chronic disorders that poorly respond to pharmacological interventions …