Progress in the development of volatile exhaled breath signatures of lung cancer

PJ Mazzone, XF Wang, S Lim, J Jett, H Choi… - Annals of the …, 2015 - atsjournals.org
Rationale: Volatile organic compounds present in the exhaled breath have shown promise
as biomarkers of lung cancer. Advances in colorimetric sensor array technology, breath …

A new strategy based on real-time secondary electrospray ionization and high-resolution mass spectrometry to discriminate endogenous and exogenous compounds …

C Berchtold, L Meier, R Steinhoff, R Zenobi - Metabolomics, 2014 - Springer
Breath is considered to be an easily accessible matrix, whose chemical composition relates
to compounds present in blood. Therefore many metabolites are expected in exhaled …

Fingerprinting breast cancer vs. normal mammary cells by mass spectrometric analysis of volatiles

J He, PML Sinues, M Hollmén, X Li, M Detmar… - Scientific reports, 2014 - nature.com
There is increasing interest in the development of noninvasive diagnostic methods for early
cancer detection, to improve the survival rate and quality of life of cancer patients …

Noninvasive detection of colorectal cancer by analysis of exhaled breath

C Wang, C Ke, X Wang, C Chi, L Guo, S Luo… - Analytical and …, 2014 - Springer
There has been growing interest in exhaled breath analysis for cancer screening and
disease monitoring; however, limited breath biomarker information exists regarding …

Comparison of targeted and untargeted approaches in breath analysis for the discrimination of lung cancer from benign pulmonary diseases and healthy persons

M Koureas, D Kalompatsios, GD Amoutzias… - Molecules, 2021 - mdpi.com
The aim of the present study was to compare the efficiency of targeted and untargeted
breath analysis in the discrimination of lung cancer (Ca+) patients from healthy people (HC) …

GC-MS-based metabolomics of volatile organic compounds in exhaled breath: Applications in health and disease. A review

M Bajo-Fernández, ÉA Souza-Silva… - Frontiers in Molecular …, 2024 - frontiersin.org
Exhaled breath analysis, with particular emphasis on volatile organic compounds,
represents a growing area of clinical research due to its obvious advantages over other …

Exhaled breath analysis for lung cancer detection using ion mobility spectrometry

H Handa, A Usuba, S Maddula, JI Baumbach… - PloS one, 2014 - journals.plos.org
Background Conventional methods for lung cancer detection including computed
tomography (CT) and bronchoscopy are expensive and invasive. Thus, there is still a need …

The metabolomic detection of lung cancer biomarkers in sputum

SJS Cameron, KE Lewis, M Beckmann, GG Allison… - Lung Cancer, 2016 - Elsevier
Objectives Developing screening and diagnosis methodologies based on novel biomarkers
should allow for the detection of the lung cancer (LC) and possibly at an earlier stage and …

[HTML][HTML] Detection of cancer through exhaled breath: a systematic review

A Krilaviciute, JA Heiss, M Leja, J Kupcinskas… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Background Timely diagnosis of cancer represents a challenging task; in particular, there is
a need for reliable non-invasive screening tools that could achieve high levels of adherence …

Volatile organic compounds and the potential for a lung cancer breath test

O Barash, U Tisch, H Haick - Lung Cancer Management, 2013 - Taylor & Francis
Detecting exhaled volatile organic compounds (VOCs) that are associated with lung cancer
(LC) has realistic potential for becoming an integral part of population-based LC screening …