Critical review of volatile organic compound analysis in breath and in vitro cell culture for detection of lung cancer

Z Jia, A Patra, VK Kutty, T Venkatesan - Metabolites, 2019 - mdpi.com
Breath analysis is a promising technique for lung cancer screening. Despite the rapid
development of breathomics in the last four decades, no consistent, robust, and validated …

Volatile organic compounds in exhaled breath as fingerprints of lung cancer, asthma and COPD

IA Ratiu, T Ligor, V Bocos-Bintintan… - Journal of clinical …, 2020 - mdpi.com
Lung cancer, chronic obstructive pulmonary disease (COPD) and asthma are inflammatory
diseases that have risen worldwide, posing a major public health issue, encompassing not …

Exhaled breath volatile organic compound biomarkers in lung cancer

PJ Mazzone - Journal of Breath Research, 2012 - iopscience.iop.org
There has been an increased focus on the development of non-invasive biomarkers capable
of accurately identifying lung cancer early in its course and characterizing the nature of the …

[HTML][HTML] Accuracy and methodologic challenges of volatile organic compound–based exhaled breath tests for cancer diagnosis: a systematic review and meta …

GB Hanna, PR Boshier, SR Markar, A Romano - JAMA oncology, 2019 - jamanetwork.com
Importance The detection and quantification of volatile organic compounds (VOCs) within
exhaled breath have evolved gradually for the diagnosis of cancer. The overall diagnostic …

Validating SIFT-MS analysis of volatiles in breath

M Storer, J Dummer, S Sturney… - Current Analytical …, 2013 - ingentaconnect.com
The ability to diagnose disease or monitor treatment response using a breath test is an
attractive concept. However, despite a variety of analysis techniques, and a growing body of …

Calculated indices of volatile organic compounds (VOCs) in exhalation for lung cancer screening and early detection

X Chen, KG Muhammad, C Madeeha, W Fu, L Xu, Y Hu… - Lung Cancer, 2021 - Elsevier
Background Breath analysis is a promising noninvasive technique that offers a wide range
of opportunities to facilitate early diagnosis of lung cancer (LC). Method Exhaled breath …

A volatile biomarker in breath predicts lung cancer and pulmonary nodules

M Phillips, TL Bauer, HI Pass - Journal of Breath Research, 2019 - iopscience.iop.org
Background: previous studies have reported volatile organic compounds (VOCs) in the
breath as apparent biomarkers of lung cancer. We tested the hypothesis that a robust breath …

Optimization of volatile markers of lung cancer to exclude interferences of non-malignant disease

Y Zou, X Zhang, X Chen, Y Hu, K Ying… - Cancer …, 2014 - content.iospress.com
Background: Breath analysis became promising for noninvasive diagnosis of cancer with
sophisticated spectrometry technology introduced. Objective: This study aimed to select …

Comparative analyses of volatile organic compounds (VOCs) from patients, tumors and transformed cell lines for the validation of lung cancer-derived breath markers

W Filipiak, A Filipiak, A Sponring… - Journal of breath …, 2014 - iopscience.iop.org
Breath analysis for the purpose of non-invasive diagnosis of lung cancer has yielded
numerous candidate compounds with still questionable clinical relevance. To arrive at …

[HTML][HTML] Real-time mass spectrometric identification of metabolites characteristic of chronic obstructive pulmonary disease in exhaled breath

L Bregy, Y Nussbaumer-Ochsner, PML Sinues… - Clinical Mass …, 2018 - Elsevier
Background New mass spectrometry (MS) techniques analysing exhaled breath have the
potential to better define airway diseases. Here, we present our work to profile the volatile …