Effect of injury severity on lower urinary tract function after experimental spinal cord injury

JR Wrathall, GS Emch - Progress in brain research, 2006 - Elsevier
Lower urinary tract dysfunction is a serious burden for patients following spinal cord injury.
Patients are usually limited to treatment with urinary drainage catheters, which can lead to …

Assessment of lower urinary tract functional deficit in rats with contusive spinal cord injury

V PIKOV, RA GILLIS, LUC JASMIN… - Journal of …, 1998 - liebertpub.com
Traumatic spinal cord injury (SCI) produces lower urinary tract (LUT) dysfunction that has
been studied in surgical transection models. Our aim was to assess LUT functional deficit in …

Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity

V Pikov, JR Wrathall - Journal of Neuroscience, 2001 - Soc Neuroscience
Recovery of urinary tract function after spinal cord injury (SCI) is important in its own right
and may also serve as a model for studying mechanisms of functional recovery after injury in …

Deficits in bladder function following spinal cord injury vary depending on the level of the injury

BT David, O Steward - Experimental neurology, 2010 - Elsevier
Loss of bladder function is an important consequence of a spinal cord injury (SCI) but is
rarely assessed in animal studies of SCI. Here, we use a simple outcome measure (volume …

Changes in afferent activity after spinal cord injury

WC de Groat, N Yoshimura - Neurourology and Urodynamics …, 2010 - Wiley Online Library
Aims To summarize the changes that occur in the properties of bladder afferent neurons
following spinal cord injury. Methods Literature review of anatomical, immunohistochemical …

[HTML][HTML] Slow development of bladder malfunction parallels spinal cord fiber sprouting and interneurons' loss after spinal cord transection

AM Sartori, AS Hofer, MI Scheuber, R Rust… - Experimental …, 2022 - Elsevier
Neurogenic lower urinary tract dysfunction typically develops after spinal cord injury. We
investigated the time course and the anatomical changes in the spinal cord that may be …

Lower urinary tract function in spinal cord-injured rats: midthoracic contusion versus transection

T Mitsui, M Murray, K Nonomura - Spinal Cord, 2014 - nature.com
Objectives: To compare changes in lower urinary tract (LUT) function with modifications in
pathways that regulate LUT function using two different animal models (incomplete and …

Mechanisms underlying the recovery of lower urinary tract function following spinal cord injury

WC De Groat - Spinal Cord, 1995 - nature.com
The functions of the lower urinary tract to store and periodically release urine are dependent
upon neural circuits located in the brain, spinal cord and peripheral ganglia_ 1, 2 This …

Characterization of lower urinary tract dysfunction after thoracic spinal cord injury in Yucatan Minipigs

MS Keung, F Streijger, A Herrity, J Ethridge… - Journal of …, 2021 - liebertpub.com
There is an increasing need to develop approaches that will not only improve the clinical
management of neurogenic lower urinary tract dysfunction (NLUTD) after spinal cord injury …

Comparison of the effects of complete and incomplete spinal cord injury on lower urinary tract function as evaluated in unanesthetized rats

PY Leung, CS Johnson, JR Wrathall - Experimental neurology, 2007 - Elsevier
In rats, phasic external urethral sphincter (EUS) activity (bursting) is postulated to be crucial
for efficient voiding. This has been reported to be lost after spinal cord transection (txSCI) …