AGRP neurons modulate fasting-induced anxiolytic effects

C Li, Y Hou, J Zhang, G Sui, X Du, J Licinio… - Translational …, 2019 - nature.com
Recent studies indicate that activation of hypothalamic Agouti-related protein (Agrp) neurons
can increase forage-related/repetitive behavior and decrease anxiety levels. However, the …

De novo neurogenesis in adult hypothalamus as a compensatory mechanism to regulate energy balance

AA Pierce, AW Xu - Journal of Neuroscience, 2010 - Soc Neuroscience
The ability to develop counter-regulatory mechanisms to maintain energy balance in
response to environmental and physiologic insults is essential for survival, but the …

AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors

MO Dietrich, J Bober, JG Ferreira, LA Tellez… - Nature …, 2012 - nature.com
It is not known whether behaviors unrelated to feeding are affected by hypothalamic
regulators of hunger. We found that impairment of Agouti-related protein (AgRP) circuitry by …

Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales

Y Mandelblat-Cerf, RN Ramesh, CR Burgess, P Patella… - Elife, 2015 - elifesciences.org
Agouti-related-peptide (AgRP) neurons—interoceptive neurons in the arcuate nucleus of the
hypothalamus (ARC)—are both necessary and sufficient for driving feeding behavior. To …

[PDF][PDF] Preemptive stimulation of AgRP neurons in fed mice enables conditioned food seeking under threat

N Jikomes, RN Ramesh, Y Mandelblat-Cerf… - Current Biology, 2016 - cell.com
The decision to engage in food-seeking behavior depends not only on homeostatic signals
related to energy balance [1] but also on the presence of competing motivational drives [2] …

The relevance of AgRP neuron-derived GABA inputs to POMC neurons differs for spontaneous and evoked release

AR Rau, ST Hentges - Journal of Neuroscience, 2017 - Soc Neuroscience
Hypothalamic agouti-related peptide (AgRP) neurons potently stimulate food intake,
whereas proopiomelanocortin (POMC) neurons inhibit feeding. Whether AgRP neurons …

Hypothalamic neuropeptide expression following chronic food restriction in sedentary and wheel-running rats

CE De Rijke, JJG Hillebrand… - Journal of …, 2005 - jme.bioscientifica.com
When rats are given access to a running-wheel in combination with food restriction, they will
become hyperactive and decrease their food intake, a paradoxical phenomenon known as …

Activation of Agrp neurons modulates memory-related cognitive processes in mice

MR Zimmer, AE Schmitz, MO Dietrich - Pharmacological research, 2019 - Elsevier
Hypothalamic Agrp neurons are critical regulators of food intake in adult mice. In addition to
food intake, these neurons have been involved in other cognitive processes, such as the …

Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum

A Reichenbach, RE Clarke, R Stark, SH Lockie… - Elife, 2022 - elifesciences.org
Agouti-related peptide (AgRP) neurons increase motivation for food, however, whether
metabolic sensing of homeostatic state in AgRP neurons potentiates motivation by …

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

Y Aponte, D Atasoy, SM Sternson - Nature neuroscience, 2011 - nature.com
Two intermingled hypothalamic neuron populations specified by expression of agouti-
related peptide (AGRP) or pro-opiomelanocortin (POMC) positively and negatively influence …