Untitled Page 1 Page 2 THE ROLE OF ACE I/D AND AGT M235T GENETIC POLYMORPHISMS
ON THE ONSET OF ESSENTIAL (PRIMARY) HYPERTENSION IN JORDANIAN POPULATION …

Genetic, environmental and demographic factors contribute to the development of essential
hypertension. Genetic polymorphism of Rennin-angiotensin-aldosterone system (RAAS) has …

Objective: Essential or primary hypertension in developing countries has become a major
problem. Recent hypertension-related research has revealed susceptibility genes in …

Background: Essential hypertension is a complex polygenic disorder arising from the
interaction of several genes with environmental factors. Of the various physiological …

The association of angiotensin converting enzyme (ACE) gene insertion/deletion (I/D)
polymorphism with hypertension has not been confirmed. Inconsistencies may be due to the …

Essential hypertension is an important risk factor for the development of cardiovascular
disease. We aim in this study to analyse the relationship between AGT M235T gene variant …

Essential hypertension is a complex polygenic disorder influenced by many environmental
factors. Previous studies have demonstrated that angiotensin converting enzyme (ACE) …

Several studies in different populations have shown mixed association of hypertension with
ACE I/D and G2350A polymorphisms. To assess the link of these two polymorphisms with …

Genetic variants of renin angiotensin system (RAS) gene play a significant role in the
pathogenesis of essential hypertension and cardiovascular diseases. In the present study …

Studies in spontaneously hypertensive rat had revealed an elevated level of ACE gene
expression in the tissues and is substantiated by experimental clinical studies for a positive …