Synchrotron X-ray sources have unique capabilities for in vivo imaging of the lungs in small
animals. The moving, breathing lungs can be captured in detail due to the high brightness …

Many lung disease processes are characterized by structural and functional heterogeneity
that is not directly appreciable with traditional physiological measurements. Experimental …

Synchrotron radiation offers unique properties of coherence, utilized in phase-contrast
imaging, and high flux as well as a wide energy spectrum which allow the selection of very …

Lung diseases are a major burden of public health especially in developed countries and
therefore continue to be an active interest in preclinical and clinical research. Due to the …

Bright synchrotron x-ray sources enable imaging with short exposure times, and hence in a
high-speed image sequence. These x-ray movies can capture not only sample structure, but …

Lungs represent the integrative part of the mammalian respiratory system, without which no
molecular processes would be possible. However, lung failure still represents one of the …

Pulmonary research is challenging because of the lack of visualization of lung airspace by
commonly used imaging modalities. Cyclic breathing and motion artifacts due to …

The complexity of lung diseases makes pre-clinical in vivo respiratory research in mouse
lungs of great importance for a better understanding of physiology and therapeutic effects …

Airway is a complex branching structure of many compliant tubes, and then airway geometry
and compliance have many biomechanical and clinical implications. In this study, we …

The high flux and coherence produced at long synchrotron beamlines makes them well
suited to performing phase-contrast X-ray imaging of the airways and lungs of live small …