Abstract Recently, TDP-43, a 43 kDa nuclear TAR DNA-binding protein, was identified as
the major disease protein in frontotemporal lobar degeneration with ubiquitinated inclusions …

The identification of the TAR DNA-binding protein 43 (TDP-43) as the ubiquitinated
cytoplasmic inclusions in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral …

TAR DNA-binding protein 43 (TDP-43) is a major pathological protein of sporadic and
familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions …

Frontotemporal lobar degeneration (FTLD) with TDP-43-immunoreactive inclusions (FTLD–
TDP) is a neurodegenerative disease associated with clinical, genetic, and …

We have investigated the extent and pattern of immunostaining for the TAR DNA-binding
protein, TDP-43, in 37 patients with frontotemporal lobar degeneration with ubiquitin (UBQ) …

TAR DNA-binding protein of 43 kDa (TDP-43) is a major component of the pathological
inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy, also called …

Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are types
of major TDP-43 (43-kDa TAR DNA-binding protein) proteinopathy. Cortical TDP-43 …

Background Recently, TAR DNA-binding protein 43 (TDP-43) was identified as the major
component of ubiquitin-positive tau-negative neuronal and glial inclusions in the most …

Importance TAR DNA-binding protein of 43 kDa (TDP-43) plays a major role in the
pathogenesis of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis …

Frontotemporal lobar degeneration (FTLD) can be pathologically subdivided into tau-
positive and tau-negative types. The most common tau-negative variant is FTLD with …