The dual effect of the particulate and organic components of diesel exhaust particles on the alteration of pulmonary immune/inflammatory responses and metabolic …

JYC Ma, JKH Ma - Journal of Environmental Science and Health …, 2002 - Taylor & Francis
Exposure to diesel exhaust particles (DEP) is an environmental and occupational health
concern. This review examines the cellular actions of the organic and the particulate …

Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages

N Li, M Wang, TD Oberley, JM Sempf… - The Journal of …, 2002 - journals.aai.org
Inhaled diesel exhaust particles (DEP) exert proinflammatory effects in the respiratory tract.
This effect is related to the particle content of redox cycling chemicals and is involved in the …

Effect of diesel exhaust particulate (DEP) on immune responses: contributions of particulate versus organic soluble components

PD Siegel, RK Saxena, QB Saxena… - Journal of Toxicology …, 2004 - Taylor & Francis
The effect of diesel exhaust particulate (DEP) exposure on innate, cellular and humoral
pulmonary immunity was studied using high-dose, acute-exposure rat, mouse, and cell …

Diesel exhaust particles and their effect on induced cytokine expression in human bronchial epithelial cells

H Takizawa - Current opinion in allergy and clinical immunology, 2004 - journals.lww.com
Host responses to DEPs are regulated by a balance between antioxidants and
proinflammatory responses. DEP-induced oxidants play a key role in proinflammatory …

Chemicals in diesel exhaust particles generate reactive oxygen radicals and induce apoptosis in macrophages

TS Hiura, MP Kaszubowski, N Li… - The Journal of …, 1999 - journals.aai.org
There is increasing evidence that particulate air pollutants, such as diesel exhaust particles
(DEP), potentiate chronic inflammatory processes as well as acute symptomatic responses …

Respiratory health effects of diesel particulate matter

ZD Ristovski, B Miljevic, NC Surawski… - …, 2012 - Wiley Online Library
Particulate matter (PM) emissions involve a complex mixture of solid and liquid particles
suspended in a gas, where it is noted that PM emissions from diesel engines are a major …

Role of oxidative stresses induced by diesel exhaust particles in airway inflammation, allergy and asthma: their potential as a target of chemoprevention

YJ Li, H Takizawa, T Kawada - Inflammation & Allergy-Drug …, 2010 - ingentaconnect.com
Epidemiological studies have shown that particulate air pollutants, such as diesel exhaust
particles (DEPs) are implicated in the increased incidence of allergic airway disorders. DEPs …

Involvement of reactive oxygen species in the metabolic pathways triggered by diesel exhaust particles in human airway epithelial cells

A Baulig, M Garlatti, V Bonvallot… - … of Physiology-Lung …, 2003 - journals.physiology.org
Diesel exhaust particles (DEP) induce a proinflammatory response in human bronchial
epithelial cells (16HBE) characterized by the release of proinflammatory cytokines after …

Inflammation‐Related Effects of Diesel Engine Exhaust Particles: Studies on Lung Cells In Vitro

PE Schwarze, AI Totlandsdal, M Låg… - BioMed research …, 2013 - Wiley Online Library
Diesel exhaust and its particles (DEP) have been under scrutiny for health effects in
humans. In the development of these effects inflammation is regarded as a key process …

Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial …

S Kawasaki, H Takizawa, K Takami… - American journal of …, 2001 - atsjournals.org
Epidemiologic and experimental studies suggest that diesel exhaust particles (DEPs) may
be related to increasing respiratory mortality and morbidity. We have shown that DEPs …