Evolving Characteristics of Heart Transplantation Donors and Recipients: JACC Focus Seminar

EM DeFilippis, KK Khush, MA Farr, A Fiedler… - Journal of the American …, 2022 - jacc.org
Although the burden of end-stage heart failure continues to increase, the number of
available organs for heart transplantation (HT) remains inadequate. The HT community has …

[HTML][HTML] Donor selection in the modern era

KK Khush - Annals of cardiothoracic surgery, 2018 - ncbi.nlm.nih.gov
The growing disparity between the supply of donor hearts for transplantation and the
demand for such organs has led to liberalization of the criteria for donor heart acceptance …

[HTML][HTML] Great variability in donor heart acceptance practices across the United States

KK Khush, RL Ball - American Journal of Transplantation, 2020 - Elsevier
Disparities in organ acceptance practices exacerbate donor heart nonuse and lead to
increased waiting times and mortality for heart transplant candidates. We studied disparities …

[HTML][HTML] The future of cardiac transplantation

K Koomalsingh, JA Kobashigawa - Annals of Cardiothoracic …, 2018 - ncbi.nlm.nih.gov
The first human-to-human heart transplant was performed 50 years ago in 1967. Heart
transplantation has now entered an era of tremendous growth and innovation. The future of …

Heart transplantation: advances in expanding the donor pool and xenotransplantation

S Jou, SR Mendez, J Feinman, LR Mitrani… - Nature Reviews …, 2024 - nature.com
Approximately 65 million adults globally have heart failure, and the prevalence is expected
to increase substantially with ageing populations. Despite advances in pharmacological and …

Current use of hearts from hepatitis C viremic donors: a United Network for Organ Sharing registry analysis

Y Moayedi, CPS Fan, AF Gulamhusein… - Circulation: Heart …, 2018 - Am Heart Assoc
Background: Strategies to improve donor heart utilization are required in the setting of
limited donor availability. One innovative strategy is to consider the use of hepatitis C viremic …

Heart donation and preservation: historical perspectives, current technologies, and future directions

NR Hess, LA Ziegler, DJ Kaczorowski - Journal of Clinical Medicine, 2022 - mdpi.com
Heart transplantation has become the accepted treatment for advanced heart failure, with
over 4000–5000 performed in the world annually. Although the number of yearly transplants …

Innovations in heart transplantation: a review

AC Coniglio, CB Patel, M Kittleson, K Schlendorf… - Journal of Cardiac …, 2022 - Elsevier
Advanced heart failure affects tens of thousands of people in the United States alone with
high morbidity and mortality. Cardiac transplantation offers the best treatment strategy, but …

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 37th adult heart transplantation report—2020; …

KK Khush, L Potena, WS Cherikh… - The Journal of Heart …, 2020 - jhltonline.org
Heart transplantation continues to be limited by a paucity of donor organs despite
innovations in organ procurement and organ preservation, greater willingness to accept …

New approaches to donor selection and preparation in heart transplantation

CKW Tong, KK Khush - Current Treatment Options in Cardiovascular …, 2021 - Springer
Purpose of review With increasing survival of patients with stage D heart failure, the demand
for heart transplantation has increased. The supply of donor hearts remains relatively …