Objective: This study examined the changes in synovial fluid levels of cytokines, oxidative
stress and viscosity six months after intraarticular hyaluronic acid (HA) treatment in adults …

Background The changes in synovial fluid biomarkers after intra-articular injection of
hyarulonic acid (IA HA) remain controversial. We investigate the changes in the properties of …

OBJECTIVE: Intraarticular (IA) hylan injections constitute second-line therapy for
osteoarthritis (OA) of the knee, but human studies suggesting a possible mechanism of …

Aim To evaluate the therapeutic trajectory of intra‐articular injections of hyaluronic acid at
high concentration (2%) performed at 4‐month intervals. Methods Subjects with knee …

OBJECTIVE To determine whether viscosupplementation with intra-articular hyaluronic acid
(HA) injections improves pain and function in patients with osteoarthritis (OA) in their knees …

Intra-articular hyaluronic acid viscosupplementation is gaining popularity as a treatment
option in the nonoperative management of patients with osteoarthritis. Recent clinical …

Viscosupplementation is a symptomatic treatment of osteoarthritis (OA) intended to restore
rheologic homeostasis of the synovial fluid by injecting hyaluronic acid intraarticularly …

Viscosupplementation refers to the intra-articular injection of hyaluronic acid (HA) as a
hyaluronate to relieve pain and improve function, usually in patients with knee OA. HA is the …

Osteoarthritis (OA) of the knee is a chronic and progressive disease that is the product of
failure of the joint to repair cartilage breakdown and wear. This article reviews the …

Background: Knee osteoarthritis (OA) is an incurable joint disorder, representing a major
public health issue. Among options for symptom control, viscosupplementation with …