Consistent efficacy and tolerability of almotriptan in the acute treatment of multiple migraine attacks: results of a large, randomized, double-blind, placebo-controlled …

J Pascual, RM Falk, F Piessens, A Prusinski… - …, 2000 - journals.sagepub.com
In this double-blind study, the efficacy and tolerability of a single dose of almotriptan (6.25 or
12.5 mg) was compared with placebo in the treatment of three consecutive migraine attacks …

Efficacy, speed of action and tolerability of almotriptan in the acute treatment of migraine: pooled individual patient data from four randomized, double-blind, placebo …

CG Dahlöf, J Pascual, DW Dodick… - Cephalalgia, 2006 - journals.sagepub.com
A meta-analysis of pooled individual patient data from four randomized, placebo-controlled,
double-blind trials comparing several doses of almotriptan (n= 1908) with placebo (n= 386) …

Early intervention with almotriptan improves sustained pain‐free response in acute migraine

NT Mathew - Headache: The Journal of Head and Face Pain, 2003 - Wiley Online Library
Objective.—To determine whether treatment of migraine with almotriptan, when pain
intensity is mild, improves 1‐and 2‐hour pain‐free and sustained pain‐free rates compared …

A long‐term open‐label study of oral almotriptan 12.5 mg for the treatment of acute migraine

NT Mathew… - Headache: The Journal …, 2002 - Wiley Online Library
Objective.—Evaluate the long‐term tolerability of almotriptan 12.5 mg for the treatment of
acute migraine attacks occurring over a 6‐month period. Background.—Almotriptan is a …

Almotriptan improves response rates when treatment is within 1 hour of migraine onset

AJ Dowson, H Massiou, JM Lainez… - … : The Journal of Head …, 2004 - Wiley Online Library
Background.—Results from open‐label trials with almotriptan and sumatriptan have shown
higher response rates when treatment was initiated early after acute migraine onset …

Almotriptan increases sustained pain‐free outcomes in acute migraine: results from three controlled clinical trials

DW Dodick - Headache: The Journal of Head and Face Pain, 2002 - Wiley Online Library
Objective.—Evaluate the effect of almotriptan on sustained pain‐free outcome in patients
with acute migraine. Methods.—Three randomized, double‐blind, placebo‐controlled trials …

Almotriptan is an effective and well-tolerated treatment for migraine pain: results of a randomized, double-blind, placebo-controlled clinical trial

AJ Dowson, H Massiou, JM Lainez… - …, 2002 - journals.sagepub.com
Almotriptan is a novel and specific serotonin 5-HT1B/1D agonist for the acute treatment of
migraine. This randomized, single-dose, double-blind, multicentre, study assessed the …

Meta‐analysis examining the efficacy and safety of almotriptan in the acute treatment of migraine

LC Chen, DM Ashcroft - Headache: The Journal of Head and …, 2007 - Wiley Online Library
Objective.—To evaluate the comparative efficacy and safety of oral almotriptan in treating
acute migraine attacks. Background.—Almotriptan is an oral selective sertonin1B/1D …

How does almotriptan compare with other triptans? A review of data from placebo‐controlled clinical trials

CGH Dahlöf, D Dodick, AJ Dowson… - … : The Journal of Head …, 2002 - Wiley Online Library
Almotriptan, the new selective 5‐HT1B/1D agonist, has a higher oral bioavailability than any
other triptan, with more than two thirds of the administered dose absorbed within the first …

Early Intervention With Almotriptan: Results of the AEGIS Trial (AXERT® Early Migraine Intervention Study)

NT Mathew, G Finlayson, TR Smith… - … : The Journal of …, 2007 - Wiley Online Library
Objective.—To evaluate prospectively the efficacy and safety of almotriptan 12.5 mg as
compared to placebo when administered within 1 hour of headache pain onset for the acute …