Werner syndrome (WS), also known as adult progeria, is extremely rare, with about 1300
known cases in the world, with over 1000 of these in Japan. It occurs due to loss of function …

Werner syndrome (WS) is an autosomal recessive progeroid disorder caused by mutations
in RecQ DNA helicase. Ectopic soft tissue calcification is one of the well known symptoms in …

Segmental progeroid syndromes are groups of genetic disorders with multiple features
resembling accelerated aging. The International Registry of Werner Syndrome (Seattle, WA) …

Progeroid syndrome is a group of disorders characterized by the early onset of diseases that
are associated with aging. Best known examples are Werner syndrome, which is adult onset …

ABSTRACT Werner's syndrome (WS), a representative progeroid syndrome with
chromosomal instability caused by the mutation of RecQ type DNA/RNA helicase, manifests …

Werner's syndrome, also known as" progeria adultorum", manifests itself in young adults.
They appear older than their chronological age. Characteristically, there is atrophy in the …

Ingegnoli and Crotti 247 abnormalities were consistent with a scleroderma-like pattern
characterized by disorganization of capillary architecture: giant, tortuous and crossing …

Progeroid syndromes have been the focus of intense research in part because they might
provide a window into the pathology of normal ageing. Werner syndrome and Hutchinson …

Werner syndrome (WS) is a rare, adult-onset progeroid syndrome. Classic WS is caused by
WRN mutation and partial atypical WS (AWS) is caused by LMNA mutation. A 19-year-old …

Werner syndrome (WS) is a prototypical segmental progeroid syndrome characterized by
multiple features consistent with accelerated aging. It is caused by null mutations of the …